Mitochondrial Redox Hubs as Promising Targets for Anticancer Therapy

Mitochondrial Redox Hubs as Promising Targets for Anticancer Therapy

Mitochondria play multifaceted roles in malignant tumor progression. Beyond their bioenergetic role, mitochondria are essential for providing malignant cells a higher plasticity to face the harsh environmental conditions. Cell-autonomous metabolic deregulation of cancer cells, or metabolic adaptatio...

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Bibliographic Details
Main Authors: Luigi Ippolito, Elisa Giannoni, Paola Chiarugi, Matteo Parri
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Oncology
Subjects:
mitochondria
ROS—reactive oxygen species
tumor microenviroment
anti oxidant
anticancer activity
redox targeting
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00256/full

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