Alu and b1 repeats have been selectively retained in the upstream and intronic regions of genes of specific functional classes.
Alu and B1 repeats are mobile elements that originated in an initial duplication of the 7SL RNA gene prior to the primate-rodent split about 80 million years ago and currently account for a substantial fraction of the human and mouse genome, respectively. Following the primate-rodent split, Alu and...
Main Authors: | Aristotelis Tsirigos, Isidore Rigoutsos |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-12-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC2784220?pdf=render |
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