Tuberculosis lymphadenitis in a south-eastern region in Tunisia: Epidemiology, clinical features, diagnosis and treatment
Aim: To evaluate patients’ profiles, demographics, clinical and therapeutic approaches and strategies in patients with tuberculous lymphadenitis (TBG). Patients and methods: A retrospective study of all TBG-confirmed cases admitted in a tuberculosis specific health care facility between 1 January 20...
Main Authors: | , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2015-01-01
|
Series: | International Journal of Mycobacteriology |
Subjects: | |
Online Access: | http://www.ijmyco.org/article.asp?issn=2212-5531;year=2015;volume=4;issue=5;spage=151;epage=151;aulast=Smaoui;type=0 |
_version_ | 1819291216579133440 |
---|---|
author | S Smaoui M A Mezghanni B Hammami N Zalila C Marouane S Kammoun A Ghorbel M Ben Jemaa F Messadi-Akrout |
author_facet | S Smaoui M A Mezghanni B Hammami N Zalila C Marouane S Kammoun A Ghorbel M Ben Jemaa F Messadi-Akrout |
author_sort | S Smaoui |
collection | DOAJ |
description | Aim: To evaluate patients’ profiles, demographics, clinical and therapeutic approaches and strategies in patients with tuberculous lymphadenitis (TBG).
Patients and methods: A retrospective study of all TBG-confirmed cases admitted in a tuberculosis specific health care facility between 1 January 2009 and 16 June 2013.
Results: A total of 181 clinical files were examined. Mean age was 32 years old; the female/male ratio was 1.78 to 1. Raw milk consumption was noted in 1/3 of patients. Most cases involved the head and neck region (83.4%), nodes involvement, including axillary (12 cases), and mediastinal (9 cases). Clinical symptoms were present in only 55.2%. TST was conducted with 82.6% positive responses. Diagnostics confirmation was done with anatomical pathology in most of the patients; only 56 of them had any microbiology analysis done. Demonstration of acid-fast bacilli in microscopy from either fine-needle aspirates or biopsies was done in 17.5%, and cultures yielded positive results in 27%. Treatment duration was varied. Paradoxical reactions were noted in 12% and persistent lymphadenopathy after treatment completion was noted in 10% of cases.
Conclusions: TBG remains a disease of interest. Today, its diagnosis and management is still a problem despite its increasing worldwide incidence, and especially in this study area. Disease control should be strengthened in this country. |
first_indexed | 2024-12-24T03:35:07Z |
format | Article |
id | doaj.art-e96e45b61fd54e24af7cfc7ad3b0326f |
institution | Directory Open Access Journal |
issn | 2212-5531 2212-554X |
language | English |
last_indexed | 2024-12-24T03:35:07Z |
publishDate | 2015-01-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | International Journal of Mycobacteriology |
spelling | doaj.art-e96e45b61fd54e24af7cfc7ad3b0326f2022-12-21T17:17:06ZengWolters Kluwer Medknow PublicationsInternational Journal of Mycobacteriology2212-55312212-554X2015-01-0145151151Tuberculosis lymphadenitis in a south-eastern region in Tunisia: Epidemiology, clinical features, diagnosis and treatmentS SmaouiM A MezghanniB HammamiN ZalilaC MarouaneS KammounA GhorbelM Ben JemaaF Messadi-AkroutAim: To evaluate patients’ profiles, demographics, clinical and therapeutic approaches and strategies in patients with tuberculous lymphadenitis (TBG). Patients and methods: A retrospective study of all TBG-confirmed cases admitted in a tuberculosis specific health care facility between 1 January 2009 and 16 June 2013. Results: A total of 181 clinical files were examined. Mean age was 32 years old; the female/male ratio was 1.78 to 1. Raw milk consumption was noted in 1/3 of patients. Most cases involved the head and neck region (83.4%), nodes involvement, including axillary (12 cases), and mediastinal (9 cases). Clinical symptoms were present in only 55.2%. TST was conducted with 82.6% positive responses. Diagnostics confirmation was done with anatomical pathology in most of the patients; only 56 of them had any microbiology analysis done. Demonstration of acid-fast bacilli in microscopy from either fine-needle aspirates or biopsies was done in 17.5%, and cultures yielded positive results in 27%. Treatment duration was varied. Paradoxical reactions were noted in 12% and persistent lymphadenopathy after treatment completion was noted in 10% of cases. Conclusions: TBG remains a disease of interest. Today, its diagnosis and management is still a problem despite its increasing worldwide incidence, and especially in this study area. Disease control should be strengthened in this country.http://www.ijmyco.org/article.asp?issn=2212-5531;year=2015;volume=4;issue=5;spage=151;epage=151;aulast=Smaoui;type=0Tuberculous lymphadenitisEpidemiologyMicrobiologyTreatmentTunisia |
spellingShingle | S Smaoui M A Mezghanni B Hammami N Zalila C Marouane S Kammoun A Ghorbel M Ben Jemaa F Messadi-Akrout Tuberculosis lymphadenitis in a south-eastern region in Tunisia: Epidemiology, clinical features, diagnosis and treatment International Journal of Mycobacteriology Tuberculous lymphadenitis Epidemiology Microbiology Treatment Tunisia |
title | Tuberculosis lymphadenitis in a south-eastern region in Tunisia: Epidemiology, clinical features, diagnosis and treatment |
title_full | Tuberculosis lymphadenitis in a south-eastern region in Tunisia: Epidemiology, clinical features, diagnosis and treatment |
title_fullStr | Tuberculosis lymphadenitis in a south-eastern region in Tunisia: Epidemiology, clinical features, diagnosis and treatment |
title_full_unstemmed | Tuberculosis lymphadenitis in a south-eastern region in Tunisia: Epidemiology, clinical features, diagnosis and treatment |
title_short | Tuberculosis lymphadenitis in a south-eastern region in Tunisia: Epidemiology, clinical features, diagnosis and treatment |
title_sort | tuberculosis lymphadenitis in a south eastern region in tunisia epidemiology clinical features diagnosis and treatment |
topic | Tuberculous lymphadenitis Epidemiology Microbiology Treatment Tunisia |
url | http://www.ijmyco.org/article.asp?issn=2212-5531;year=2015;volume=4;issue=5;spage=151;epage=151;aulast=Smaoui;type=0 |
work_keys_str_mv | AT ssmaoui tuberculosislymphadenitisinasoutheasternregionintunisiaepidemiologyclinicalfeaturesdiagnosisandtreatment AT mamezghanni tuberculosislymphadenitisinasoutheasternregionintunisiaepidemiologyclinicalfeaturesdiagnosisandtreatment AT bhammami tuberculosislymphadenitisinasoutheasternregionintunisiaepidemiologyclinicalfeaturesdiagnosisandtreatment AT nzalila tuberculosislymphadenitisinasoutheasternregionintunisiaepidemiologyclinicalfeaturesdiagnosisandtreatment AT cmarouane tuberculosislymphadenitisinasoutheasternregionintunisiaepidemiologyclinicalfeaturesdiagnosisandtreatment AT skammoun tuberculosislymphadenitisinasoutheasternregionintunisiaepidemiologyclinicalfeaturesdiagnosisandtreatment AT aghorbel tuberculosislymphadenitisinasoutheasternregionintunisiaepidemiologyclinicalfeaturesdiagnosisandtreatment AT mbenjemaa tuberculosislymphadenitisinasoutheasternregionintunisiaepidemiologyclinicalfeaturesdiagnosisandtreatment AT fmessadiakrout tuberculosislymphadenitisinasoutheasternregionintunisiaepidemiologyclinicalfeaturesdiagnosisandtreatment |