Tuberculosis lymphadenitis in a south-eastern region in Tunisia: Epidemiology, clinical features, diagnosis and treatment

Aim: To evaluate patients’ profiles, demographics, clinical and therapeutic approaches and strategies in patients with tuberculous lymphadenitis (TBG). Patients and methods: A retrospective study of all TBG-confirmed cases admitted in a tuberculosis specific health care facility between 1 January 20...

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Main Authors: S Smaoui, M A Mezghanni, B Hammami, N Zalila, C Marouane, S Kammoun, A Ghorbel, M Ben Jemaa, F Messadi-Akrout
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:International Journal of Mycobacteriology
Subjects:
Online Access:http://www.ijmyco.org/article.asp?issn=2212-5531;year=2015;volume=4;issue=5;spage=151;epage=151;aulast=Smaoui;type=0
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author S Smaoui
M A Mezghanni
B Hammami
N Zalila
C Marouane
S Kammoun
A Ghorbel
M Ben Jemaa
F Messadi-Akrout
author_facet S Smaoui
M A Mezghanni
B Hammami
N Zalila
C Marouane
S Kammoun
A Ghorbel
M Ben Jemaa
F Messadi-Akrout
author_sort S Smaoui
collection DOAJ
description Aim: To evaluate patients’ profiles, demographics, clinical and therapeutic approaches and strategies in patients with tuberculous lymphadenitis (TBG). Patients and methods: A retrospective study of all TBG-confirmed cases admitted in a tuberculosis specific health care facility between 1 January 2009 and 16 June 2013. Results: A total of 181 clinical files were examined. Mean age was 32 years old; the female/male ratio was 1.78 to 1. Raw milk consumption was noted in 1/3 of patients. Most cases involved the head and neck region (83.4%), nodes involvement, including axillary (12 cases), and mediastinal (9 cases). Clinical symptoms were present in only 55.2%. TST was conducted with 82.6% positive responses. Diagnostics confirmation was done with anatomical pathology in most of the patients; only 56 of them had any microbiology analysis done. Demonstration of acid-fast bacilli in microscopy from either fine-needle aspirates or biopsies was done in 17.5%, and cultures yielded positive results in 27%. Treatment duration was varied. Paradoxical reactions were noted in 12% and persistent lymphadenopathy after treatment completion was noted in 10% of cases. Conclusions: TBG remains a disease of interest. Today, its diagnosis and management is still a problem despite its increasing worldwide incidence, and especially in this study area. Disease control should be strengthened in this country.
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spelling doaj.art-e96e45b61fd54e24af7cfc7ad3b0326f2022-12-21T17:17:06ZengWolters Kluwer Medknow PublicationsInternational Journal of Mycobacteriology2212-55312212-554X2015-01-0145151151Tuberculosis lymphadenitis in a south-eastern region in Tunisia: Epidemiology, clinical features, diagnosis and treatmentS SmaouiM A MezghanniB HammamiN ZalilaC MarouaneS KammounA GhorbelM Ben JemaaF Messadi-AkroutAim: To evaluate patients’ profiles, demographics, clinical and therapeutic approaches and strategies in patients with tuberculous lymphadenitis (TBG). Patients and methods: A retrospective study of all TBG-confirmed cases admitted in a tuberculosis specific health care facility between 1 January 2009 and 16 June 2013. Results: A total of 181 clinical files were examined. Mean age was 32 years old; the female/male ratio was 1.78 to 1. Raw milk consumption was noted in 1/3 of patients. Most cases involved the head and neck region (83.4%), nodes involvement, including axillary (12 cases), and mediastinal (9 cases). Clinical symptoms were present in only 55.2%. TST was conducted with 82.6% positive responses. Diagnostics confirmation was done with anatomical pathology in most of the patients; only 56 of them had any microbiology analysis done. Demonstration of acid-fast bacilli in microscopy from either fine-needle aspirates or biopsies was done in 17.5%, and cultures yielded positive results in 27%. Treatment duration was varied. Paradoxical reactions were noted in 12% and persistent lymphadenopathy after treatment completion was noted in 10% of cases. Conclusions: TBG remains a disease of interest. Today, its diagnosis and management is still a problem despite its increasing worldwide incidence, and especially in this study area. Disease control should be strengthened in this country.http://www.ijmyco.org/article.asp?issn=2212-5531;year=2015;volume=4;issue=5;spage=151;epage=151;aulast=Smaoui;type=0Tuberculous lymphadenitisEpidemiologyMicrobiologyTreatmentTunisia
spellingShingle S Smaoui
M A Mezghanni
B Hammami
N Zalila
C Marouane
S Kammoun
A Ghorbel
M Ben Jemaa
F Messadi-Akrout
Tuberculosis lymphadenitis in a south-eastern region in Tunisia: Epidemiology, clinical features, diagnosis and treatment
International Journal of Mycobacteriology
Tuberculous lymphadenitis
Epidemiology
Microbiology
Treatment
Tunisia
title Tuberculosis lymphadenitis in a south-eastern region in Tunisia: Epidemiology, clinical features, diagnosis and treatment
title_full Tuberculosis lymphadenitis in a south-eastern region in Tunisia: Epidemiology, clinical features, diagnosis and treatment
title_fullStr Tuberculosis lymphadenitis in a south-eastern region in Tunisia: Epidemiology, clinical features, diagnosis and treatment
title_full_unstemmed Tuberculosis lymphadenitis in a south-eastern region in Tunisia: Epidemiology, clinical features, diagnosis and treatment
title_short Tuberculosis lymphadenitis in a south-eastern region in Tunisia: Epidemiology, clinical features, diagnosis and treatment
title_sort tuberculosis lymphadenitis in a south eastern region in tunisia epidemiology clinical features diagnosis and treatment
topic Tuberculous lymphadenitis
Epidemiology
Microbiology
Treatment
Tunisia
url http://www.ijmyco.org/article.asp?issn=2212-5531;year=2015;volume=4;issue=5;spage=151;epage=151;aulast=Smaoui;type=0
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AT bhammami tuberculosislymphadenitisinasoutheasternregionintunisiaepidemiologyclinicalfeaturesdiagnosisandtreatment
AT nzalila tuberculosislymphadenitisinasoutheasternregionintunisiaepidemiologyclinicalfeaturesdiagnosisandtreatment
AT cmarouane tuberculosislymphadenitisinasoutheasternregionintunisiaepidemiologyclinicalfeaturesdiagnosisandtreatment
AT skammoun tuberculosislymphadenitisinasoutheasternregionintunisiaepidemiologyclinicalfeaturesdiagnosisandtreatment
AT aghorbel tuberculosislymphadenitisinasoutheasternregionintunisiaepidemiologyclinicalfeaturesdiagnosisandtreatment
AT mbenjemaa tuberculosislymphadenitisinasoutheasternregionintunisiaepidemiologyclinicalfeaturesdiagnosisandtreatment
AT fmessadiakrout tuberculosislymphadenitisinasoutheasternregionintunisiaepidemiologyclinicalfeaturesdiagnosisandtreatment