Circulating tumor DNA – A potential aid in the management of chordomas

Circulating tumor DNA – A potential aid in the management of chordomas

Chordomas are a locally invasive, low-grade, CNS malignancy that are primarily found in the skull base, spine, and sacrum. They are thought to be derived from notochordal remnants and remain a significant clinical challenge due to their local invasiveness, resistance to chemoradiation, and difficult...

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Bibliographic Details
Main Authors: Stephen C. Frederico, Corbin Darling, Xiaoran Zhang, Sakibul Huq, Sameer Agnihotri, Paul A. Gardner, Carl H. Snyderman, Eric W. Wang, Georgios A. Zenonos
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Oncology
Subjects:
clivus
ctDNA
DNA
tumor
skull base
chordoma
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1016385/full

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