Triglyceride glucose index was linearly associated with abdominal aortic calcification based on NHANES 2013–2014

Abstract Purpose To study the relationship between the TyG index and the risk of AAC. Methods We enrolled 1,486 participants from the National Health and Nutrition Examination Survey (NHANES). The TyG index was calculated in the log-transformed of triglycerides multipled by glucose, and the presence...

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Main Authors: Ying Zhou, Fu Zhi, Beibei Gao, Shengen Liao
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Endocrine Disorders
Subjects:
Online Access:https://doi.org/10.1186/s12902-022-01226-w
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author Ying Zhou
Fu Zhi
Beibei Gao
Shengen Liao
author_facet Ying Zhou
Fu Zhi
Beibei Gao
Shengen Liao
author_sort Ying Zhou
collection DOAJ
description Abstract Purpose To study the relationship between the TyG index and the risk of AAC. Methods We enrolled 1,486 participants from the National Health and Nutrition Examination Survey (NHANES). The TyG index was calculated in the log-transformed of triglycerides multipled by glucose, and the presence of AAC was diagnosed as AAC score above than 0. Results Our suggested found that TyG level was positively correlated with the presence of AAC and log-transformed AAC score. After adjusted for other variables, comparing with the lowest quartile of TyG index, the highest quartile of TyG level was significantly associated with the presence of AAC (OR 2.12, 95%CI 1.05–4.35, p = 0.038) and severe AAC (OR 2.12, 95%CI 1.05–4.35, p = 0.038). Conclusions TyG index was significantly associated with the risk of AAC and severe AAC, which could be a marker in clinical practice.
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spelling doaj.art-e97862c9e3d04528af1c57d3a3b8807a2022-12-22T03:02:07ZengBMCBMC Endocrine Disorders1472-68232022-12-012211710.1186/s12902-022-01226-wTriglyceride glucose index was linearly associated with abdominal aortic calcification based on NHANES 2013–2014Ying Zhou0Fu Zhi1Beibei Gao2Shengen Liao3Department of Cardiology, The First Affiliated Hospital of Nanjing Medical UniversityDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical UniversityDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical UniversityDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical UniversityAbstract Purpose To study the relationship between the TyG index and the risk of AAC. Methods We enrolled 1,486 participants from the National Health and Nutrition Examination Survey (NHANES). The TyG index was calculated in the log-transformed of triglycerides multipled by glucose, and the presence of AAC was diagnosed as AAC score above than 0. Results Our suggested found that TyG level was positively correlated with the presence of AAC and log-transformed AAC score. After adjusted for other variables, comparing with the lowest quartile of TyG index, the highest quartile of TyG level was significantly associated with the presence of AAC (OR 2.12, 95%CI 1.05–4.35, p = 0.038) and severe AAC (OR 2.12, 95%CI 1.05–4.35, p = 0.038). Conclusions TyG index was significantly associated with the risk of AAC and severe AAC, which could be a marker in clinical practice.https://doi.org/10.1186/s12902-022-01226-wTriglyceride glucose indexAbdominal aortic calcificationInsulin resistance
spellingShingle Ying Zhou
Fu Zhi
Beibei Gao
Shengen Liao
Triglyceride glucose index was linearly associated with abdominal aortic calcification based on NHANES 2013–2014
BMC Endocrine Disorders
Triglyceride glucose index
Abdominal aortic calcification
Insulin resistance
title Triglyceride glucose index was linearly associated with abdominal aortic calcification based on NHANES 2013–2014
title_full Triglyceride glucose index was linearly associated with abdominal aortic calcification based on NHANES 2013–2014
title_fullStr Triglyceride glucose index was linearly associated with abdominal aortic calcification based on NHANES 2013–2014
title_full_unstemmed Triglyceride glucose index was linearly associated with abdominal aortic calcification based on NHANES 2013–2014
title_short Triglyceride glucose index was linearly associated with abdominal aortic calcification based on NHANES 2013–2014
title_sort triglyceride glucose index was linearly associated with abdominal aortic calcification based on nhanes 2013 2014
topic Triglyceride glucose index
Abdominal aortic calcification
Insulin resistance
url https://doi.org/10.1186/s12902-022-01226-w
work_keys_str_mv AT yingzhou triglycerideglucoseindexwaslinearlyassociatedwithabdominalaorticcalcificationbasedonnhanes20132014
AT fuzhi triglycerideglucoseindexwaslinearlyassociatedwithabdominalaorticcalcificationbasedonnhanes20132014
AT beibeigao triglycerideglucoseindexwaslinearlyassociatedwithabdominalaorticcalcificationbasedonnhanes20132014
AT shengenliao triglycerideglucoseindexwaslinearlyassociatedwithabdominalaorticcalcificationbasedonnhanes20132014