Rationales and Approaches for Studying Metabolism in Eukaryotic Microalgae
The generation of efficient production strains is essential for the use of eukaryotic microalgae for biofuel production. Systems biology approaches including metabolite profiling on promising microalgal strains, will provide a better understanding of their metabolic networks, which is crucial for m...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2014-04-01
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| Series: | Metabolites |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2218-1989/4/2/184 |
| _version_ | 1818290752052002816 |
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| author | Daniel Veyel Alexander Erban Ines Fehrle Joachim Kopka Michael Schroda |
| author_facet | Daniel Veyel Alexander Erban Ines Fehrle Joachim Kopka Michael Schroda |
| author_sort | Daniel Veyel |
| collection | DOAJ |
| description | The generation of efficient production strains is essential for the use of eukaryotic microalgae for biofuel production. Systems biology approaches including metabolite profiling on promising microalgal strains, will provide a better understanding of their metabolic networks, which is crucial for metabolic engineering efforts. Chlamydomonas reinhardtii represents a suited model system for this purpose. We give an overview to genetically amenable microalgal strains with the potential for biofuel production and provide a critical review of currently used protocols for metabolite profiling on Chlamydomonas. We provide our own experimental data to underpin the validity of the conclusions drawn. |
| first_indexed | 2024-12-13T02:33:09Z |
| format | Article |
| id | doaj.art-e97d3aa500ae4d198750cd7ac47a6b35 |
| institution | Directory Open Access Journal |
| issn | 2218-1989 |
| language | English |
| last_indexed | 2024-12-13T02:33:09Z |
| publishDate | 2014-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Metabolites |
| spelling | doaj.art-e97d3aa500ae4d198750cd7ac47a6b352022-12-22T00:02:28ZengMDPI AGMetabolites2218-19892014-04-014218421710.3390/metabo4020184metabo4020184Rationales and Approaches for Studying Metabolism in Eukaryotic MicroalgaeDaniel Veyel0Alexander Erban1Ines Fehrle2Joachim Kopka3Michael Schroda4Max Planck Institute of Molecular Plant Physiology, Am Muehlenberg 1, D-14476 Potsdam-Golm, GermanyMax Planck Institute of Molecular Plant Physiology, Am Muehlenberg 1, D-14476 Potsdam-Golm, GermanyMax Planck Institute of Molecular Plant Physiology, Am Muehlenberg 1, D-14476 Potsdam-Golm, GermanyMax Planck Institute of Molecular Plant Physiology, Am Muehlenberg 1, D-14476 Potsdam-Golm, GermanyMolecular Biotechnology & Systems Biology, Technical University of Kaiserslautern, Paul-Ehrlich-Str. 23, D-67663 Kaiserslautern, GermanyThe generation of efficient production strains is essential for the use of eukaryotic microalgae for biofuel production. Systems biology approaches including metabolite profiling on promising microalgal strains, will provide a better understanding of their metabolic networks, which is crucial for metabolic engineering efforts. Chlamydomonas reinhardtii represents a suited model system for this purpose. We give an overview to genetically amenable microalgal strains with the potential for biofuel production and provide a critical review of currently used protocols for metabolite profiling on Chlamydomonas. We provide our own experimental data to underpin the validity of the conclusions drawn.http://www.mdpi.com/2218-1989/4/2/184Chlamydomonas reinhardtiimetabolic engineeringbiofuelsmetabolite profilingGC-MSsystems biology |
| spellingShingle | Daniel Veyel Alexander Erban Ines Fehrle Joachim Kopka Michael Schroda Rationales and Approaches for Studying Metabolism in Eukaryotic Microalgae Metabolites Chlamydomonas reinhardtii metabolic engineering biofuels metabolite profiling GC-MS systems biology |
| title | Rationales and Approaches for Studying Metabolism in Eukaryotic Microalgae |
| title_full | Rationales and Approaches for Studying Metabolism in Eukaryotic Microalgae |
| title_fullStr | Rationales and Approaches for Studying Metabolism in Eukaryotic Microalgae |
| title_full_unstemmed | Rationales and Approaches for Studying Metabolism in Eukaryotic Microalgae |
| title_short | Rationales and Approaches for Studying Metabolism in Eukaryotic Microalgae |
| title_sort | rationales and approaches for studying metabolism in eukaryotic microalgae |
| topic | Chlamydomonas reinhardtii metabolic engineering biofuels metabolite profiling GC-MS systems biology |
| url | http://www.mdpi.com/2218-1989/4/2/184 |
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