The p38α mitogen-activated protein kinase as a central nervous system drug discovery target

<p>Abstract</p> <p>Protein kinases are critical modulators of a variety of cellular signal transduction pathways, and abnormal phosphorylation events can be a cause or contributor to disease progression in a variety of disorders. This has led to the emergence of protein kinases as...

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Hlavní autoři: Van Eldik Linda J, de Almeida Lucia, Borders Aaron S, Watterson D Martin
Médium: Článek
Jazyk:English
Vydáno: BMC 2008-12-01
Edice:BMC Neuroscience