A REVIEW OF MEASLES VIRUS

Measles is a highly contagious, acute febrile illness that results from infection with measles virus (MV). MV is a single-stranded, negative-sense RNA virus in the genus Morbillivirus of the family Paramyxoviridae. The wild-type MV consists of 24 genotypes, three of them (B3, D8 an H1) have dominat...

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Main Author: Ivona Danova
Format: Article
Language:English
Published: National Center of Infectious and Parasitic Diseases 2021-08-01
Series:Problems of Infectious and Parasitic Diseases
Subjects:
Online Access:https://pipd.ncipd.org/index.php/pipd/article/view/69
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author Ivona Danova
author_facet Ivona Danova
author_sort Ivona Danova
collection DOAJ
description Measles is a highly contagious, acute febrile illness that results from infection with measles virus (MV). MV is a single-stranded, negative-sense RNA virus in the genus Morbillivirus of the family Paramyxoviridae. The wild-type MV consists of 24 genotypes, three of them (B3, D8 an H1) have dominated circulation in the world. MV is transmitted by the respiratory route and illness begins with fever, cough, conjunctivitis followed by a rash and measles enanthem (Koplik spot). Laboratory confirmation of measles is provided by  serological (ELISA test for detection of IgM and IgG antibodies), molecular (detection of viral nucleic acid) and viral isolation in Vero/hSLAM cells methods. As a vaccine-preventable infection, measles has a global importance and is a target of WHO strategic goals in the  European region. Despite significant progress in measles control in recent years, it is necessary to improve the national vaccination  coverage, and the epidemiological and laboratory monitoring of the infection. High vaccination coverage across all of the population is  crucial to reach the goals of measles elimination.
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spelling doaj.art-e984241cd1854116b777795fbb83256c2023-05-16T09:17:14ZengNational Center of Infectious and Parasitic DiseasesProblems of Infectious and Parasitic Diseases0204-91552815-28082021-08-0149210.58395/pipd.v49i2.69A REVIEW OF MEASLES VIRUSIvona Danova0NCIPD Measles is a highly contagious, acute febrile illness that results from infection with measles virus (MV). MV is a single-stranded, negative-sense RNA virus in the genus Morbillivirus of the family Paramyxoviridae. The wild-type MV consists of 24 genotypes, three of them (B3, D8 an H1) have dominated circulation in the world. MV is transmitted by the respiratory route and illness begins with fever, cough, conjunctivitis followed by a rash and measles enanthem (Koplik spot). Laboratory confirmation of measles is provided by  serological (ELISA test for detection of IgM and IgG antibodies), molecular (detection of viral nucleic acid) and viral isolation in Vero/hSLAM cells methods. As a vaccine-preventable infection, measles has a global importance and is a target of WHO strategic goals in the  European region. Despite significant progress in measles control in recent years, it is necessary to improve the national vaccination  coverage, and the epidemiological and laboratory monitoring of the infection. High vaccination coverage across all of the population is  crucial to reach the goals of measles elimination. https://pipd.ncipd.org/index.php/pipd/article/view/69measles virusmorphologydiagnosisepidemiologyelimination
spellingShingle Ivona Danova
A REVIEW OF MEASLES VIRUS
Problems of Infectious and Parasitic Diseases
measles virus
morphology
diagnosis
epidemiology
elimination
title A REVIEW OF MEASLES VIRUS
title_full A REVIEW OF MEASLES VIRUS
title_fullStr A REVIEW OF MEASLES VIRUS
title_full_unstemmed A REVIEW OF MEASLES VIRUS
title_short A REVIEW OF MEASLES VIRUS
title_sort review of measles virus
topic measles virus
morphology
diagnosis
epidemiology
elimination
url https://pipd.ncipd.org/index.php/pipd/article/view/69
work_keys_str_mv AT ivonadanova areviewofmeaslesvirus
AT ivonadanova reviewofmeaslesvirus