Preso enhances mGluR1-mediated excitotoxicity by modulating the phosphorylation of mGluR1-Homer1 complex and facilitating an ER stress after traumatic brain injury
Abstract Glutamate receptor (GluR)-mediated excitotoxicity is an important mechanism causing delayed neuronal injury after traumatic brain injury (TBI). Preso, as a core scaffolding protein of postsynaptic density (PSD), is considered an important regulator during excitotoxicity and TBI and combines...
Main Authors: | Zhuoyuan Zhang, Xiangyu Gao, Zhicheng Tian, Erwan Yang, Yutao Huang, Dan Liu, Shuhui Dai, Haofuzi Zhang, Mingdong Bao, Xiaofan Jiang, Xin Li, Peng Luo |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2024-03-01
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Series: | Cell Death Discovery |
Online Access: | https://doi.org/10.1038/s41420-024-01916-5 |
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