The full-genome characterization and phylogenetic analysis of bovine herpesvirus type 1.2 isolated in China
Bovine herpesvirus type 1 (BHV-1) causes bovine respiratory disease that poses a significant threat to the cattle industry. The prevalence of BHV-1 has recently increased in China. However, the lack of information about the prevalent isolates limits the control of the disease. In this study, a novel...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2022-11-01
|
| Series: | Frontiers in Microbiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2022.1033008/full |
| _version_ | 1811191724416958464 |
|---|---|
| author | Weiqiang Guo Jia Xie Jingyi Liu Hongjun Chen Yong-Sam Jung |
| author_facet | Weiqiang Guo Jia Xie Jingyi Liu Hongjun Chen Yong-Sam Jung |
| author_sort | Weiqiang Guo |
| collection | DOAJ |
| description | Bovine herpesvirus type 1 (BHV-1) causes bovine respiratory disease that poses a significant threat to the cattle industry. The prevalence of BHV-1 has recently increased in China. However, the lack of information about the prevalent isolates limits the control of the disease. In this study, a novel strain of BHV-1 was isolated from nasal swabs of Holstein cows in 2020 in China, designated as BHV SHJS. The genome of BHV strain SHJS is 135, 102 bp in length and highly similar to strain SP1777 (KM258883.1) with an identity of 99.64%. Mutations, insertions, or deletions mainly occur in UL27, UL44, and US8, etc., relative to the different genomic coordinates. Phylogenetic tree of UL44 (gC) showed that BHV strain SHJS belongs to BHV-1.2b cluster. The result showed that the strain had a different evolutionary origin from those prevalent in China. This study will enrich our knowledge regarding BHV outbreak strains in China and contribute to the prevention and pathogenic studies of BHV-1.2. |
| first_indexed | 2024-04-11T23:40:38Z |
| format | Article |
| id | doaj.art-e991a567432444e6ae64a79f22f6cf9b |
| institution | Directory Open Access Journal |
| issn | 1664-302X |
| language | English |
| last_indexed | 2024-04-11T23:40:38Z |
| publishDate | 2022-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Microbiology |
| spelling | doaj.art-e991a567432444e6ae64a79f22f6cf9b2022-12-22T03:56:48ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2022-11-011310.3389/fmicb.2022.10330081033008The full-genome characterization and phylogenetic analysis of bovine herpesvirus type 1.2 isolated in ChinaWeiqiang Guo0Jia Xie1Jingyi Liu2Hongjun Chen3Yong-Sam Jung4MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, ChinaShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, ChinaShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, ChinaShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, ChinaMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, ChinaBovine herpesvirus type 1 (BHV-1) causes bovine respiratory disease that poses a significant threat to the cattle industry. The prevalence of BHV-1 has recently increased in China. However, the lack of information about the prevalent isolates limits the control of the disease. In this study, a novel strain of BHV-1 was isolated from nasal swabs of Holstein cows in 2020 in China, designated as BHV SHJS. The genome of BHV strain SHJS is 135, 102 bp in length and highly similar to strain SP1777 (KM258883.1) with an identity of 99.64%. Mutations, insertions, or deletions mainly occur in UL27, UL44, and US8, etc., relative to the different genomic coordinates. Phylogenetic tree of UL44 (gC) showed that BHV strain SHJS belongs to BHV-1.2b cluster. The result showed that the strain had a different evolutionary origin from those prevalent in China. This study will enrich our knowledge regarding BHV outbreak strains in China and contribute to the prevention and pathogenic studies of BHV-1.2.https://www.frontiersin.org/articles/10.3389/fmicb.2022.1033008/fullbovine herpesvirus type 1.2isolationfull genomephylogenetic analysisBHV-1.2 |
| spellingShingle | Weiqiang Guo Jia Xie Jingyi Liu Hongjun Chen Yong-Sam Jung The full-genome characterization and phylogenetic analysis of bovine herpesvirus type 1.2 isolated in China Frontiers in Microbiology bovine herpesvirus type 1.2 isolation full genome phylogenetic analysis BHV-1.2 |
| title | The full-genome characterization and phylogenetic analysis of bovine herpesvirus type 1.2 isolated in China |
| title_full | The full-genome characterization and phylogenetic analysis of bovine herpesvirus type 1.2 isolated in China |
| title_fullStr | The full-genome characterization and phylogenetic analysis of bovine herpesvirus type 1.2 isolated in China |
| title_full_unstemmed | The full-genome characterization and phylogenetic analysis of bovine herpesvirus type 1.2 isolated in China |
| title_short | The full-genome characterization and phylogenetic analysis of bovine herpesvirus type 1.2 isolated in China |
| title_sort | full genome characterization and phylogenetic analysis of bovine herpesvirus type 1 2 isolated in china |
| topic | bovine herpesvirus type 1.2 isolation full genome phylogenetic analysis BHV-1.2 |
| url | https://www.frontiersin.org/articles/10.3389/fmicb.2022.1033008/full |
| work_keys_str_mv | AT weiqiangguo thefullgenomecharacterizationandphylogeneticanalysisofbovineherpesvirustype12isolatedinchina AT jiaxie thefullgenomecharacterizationandphylogeneticanalysisofbovineherpesvirustype12isolatedinchina AT jingyiliu thefullgenomecharacterizationandphylogeneticanalysisofbovineherpesvirustype12isolatedinchina AT hongjunchen thefullgenomecharacterizationandphylogeneticanalysisofbovineherpesvirustype12isolatedinchina AT yongsamjung thefullgenomecharacterizationandphylogeneticanalysisofbovineherpesvirustype12isolatedinchina AT weiqiangguo fullgenomecharacterizationandphylogeneticanalysisofbovineherpesvirustype12isolatedinchina AT jiaxie fullgenomecharacterizationandphylogeneticanalysisofbovineherpesvirustype12isolatedinchina AT jingyiliu fullgenomecharacterizationandphylogeneticanalysisofbovineherpesvirustype12isolatedinchina AT hongjunchen fullgenomecharacterizationandphylogeneticanalysisofbovineherpesvirustype12isolatedinchina AT yongsamjung fullgenomecharacterizationandphylogeneticanalysisofbovineherpesvirustype12isolatedinchina |