HLAProfiler utilizes k-mer profiles to improve HLA calling accuracy for rare and common alleles in RNA-seq data
Abstract Background The human leukocyte antigen (HLA) system is a genomic region involved in regulating the human immune system by encoding cell membrane major histocompatibility complex (MHC) proteins that are responsible for self-recognition. Understanding the variation in this region provides imp...
| Main Authors: | , , , , , , , |
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| 格式: | 文件 |
| 语言: | English |
| 出版: |
BMC
2017-09-01
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| 丛编: | Genome Medicine |
| 主题: | |
| 在线阅读: | http://link.springer.com/article/10.1186/s13073-017-0473-6 |