Evolution of linkage and genome expansion in protocells: The origin of chromosomes.
Chromosomes are likely to have assembled from unlinked genes in early evolution. Genetic linkage reduces the assortment load and intragenomic conflict in reproducing protocell models to the extent that chromosomes can go to fixation even if chromosomes suffer from a replicative disadvantage, relativ...
Main Authors: | András Szilágyi, Viktor Péter Kovács, Eörs Szathmáry, Mauro Santos |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-10-01
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Series: | PLoS Genetics |
Online Access: | https://doi.org/10.1371/journal.pgen.1009155 |
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