Zika virus remodelled ER membranes contain proviral factors involved in redox and methylation pathways
Abstract Zika virus (ZIKV) has emerged as a global health issue, yet neither antiviral therapy nor a vaccine are available. ZIKV is an enveloped RNA virus, replicating in the cytoplasm in close association with ER membranes. Here, we isolate ER membranes from ZIKV-infected cells and determine their...
Main Authors: | Solène Denolly, Alexey Stukalov, Uladzimir Barayeu, Alina N. Rosinski, Paraskevi Kritsiligkou, Sebastian Joecks, Tobias P. Dick, Andreas Pichlmair, Ralf Bartenschlager |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-12-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-43665-6 |
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