Ketone Analog of Caffeic Acid Phenethyl Ester Exhibits Antioxidant Activity via Activation of ERK-Dependent Nrf2 Pathway

Ketone Analog of Caffeic Acid Phenethyl Ester Exhibits Antioxidant Activity via Activation of ERK-Dependent Nrf2 Pathway

Due to their robust antioxidant properties, phenolic acids and their analogs are extensively studied for their ability to activate cellular antioxidant pathways, including nuclear factor (erythroid-derived-2)-like 2 (Nrf2)-antioxidant response element (ARE) pathway. Caffeic, ferulic, and gallic acid...

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Bibliographic Details
Main Authors: Khushwant S. Bhullar, Manal A. Nael, Khaled M. Elokely, Jérémie A. Doiron, Luc M. LeBlanc, Grégoire Lassalle-Claux, Mohamed Salla, Fahad S. Aldawsari, Mohamed Touaibia, H. P. Vasantha Rupasinghe
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Applied Sciences
Subjects:
caffeic acid
phenolic acid
antioxidant
oxidative stress
cell signaling
Online Access:https://www.mdpi.com/2076-3417/12/6/3062

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