Structural basis of chemokine sequestration by a tick chemokine binding protein: the crystal structure of the complex between Evasin-1 and CCL3.
Chemokines are a subset of cytokines responsible for controlling the cellular migration of inflammatory cells through interaction with seven transmembrane G protein-coupled receptors. The blocking of a chemokine-receptor interaction results in a reduced inflammatory response, and represents a possib...
Main Authors: | João M Dias, Christophe Losberger, Maud Déruaz, Christine A Power, Amanda E I Proudfoot, Jeffrey P Shaw |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-12-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2796168?pdf=render |
Similar Items
-
A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins
by: Lee, A, et al.
Published: (2019) -
Evasins: tick salivary proteins that inhibit mammalian chemokines
by: Bhusal, R, et al.
Published: (2019) -
Evasins: therapeutic potential of a new family of chemokine binding proteins from ticks
by: Amanda E.I. Proudfoot, et al.
Published: (2016-06-01) -
The N-terminal domain of a tick evasin is critical for chemokine binding and neutralization and confers specific binding activity to other evasins
by: Eaton, J, et al.
Published: (2018) -
Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities.
by: Singh, K, et al.
Published: (2017)