Reproducibility of the 75 g oral glucose tolerance test for the diagnosis of gestational diabetes mellitus in a sub-Saharan African population
Abstract Objective To evaluate the reproducibility of the 75 g oral glucose tolerance test and factors associated with non-reproducible results in Cameroonian pregnant women. Results Twenty-seven of the 84 participants (32.1%) who did the first oral glucose tolerance test were diagnosed with gestati...
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| Format: | Article |
| Language: | English |
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BMC
2017-11-01
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| Series: | BMC Research Notes |
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| Online Access: | http://link.springer.com/article/10.1186/s13104-017-2944-7 |
| _version_ | 1818584896257392640 |
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| author | Yvonne Nangeh Munang Jean Jacques Noubiap Celestin Danwang Julius Dohbit Sama Marcel Azabji-Kenfack Jean Claude Mbanya Eugene Sobngwi |
| author_facet | Yvonne Nangeh Munang Jean Jacques Noubiap Celestin Danwang Julius Dohbit Sama Marcel Azabji-Kenfack Jean Claude Mbanya Eugene Sobngwi |
| author_sort | Yvonne Nangeh Munang |
| collection | DOAJ |
| description | Abstract Objective To evaluate the reproducibility of the 75 g oral glucose tolerance test and factors associated with non-reproducible results in Cameroonian pregnant women. Results Twenty-seven of the 84 participants (32.1%) who did the first oral glucose tolerance test were diagnosed with gestational diabetes mellitus. There was no difference between the means of the glycaemic responses at T0 (p = 0.64), T30 (p = 0.08), T60 (p = 0.86), T90 (p = 0.51), and T120 (p = 0.34) between the two oral glucose tolerance test. Age (p = 0.001) and BMI (p = 0.001) were significantly associated with non-reproducible results. The reproducibility of the oral glucose tolerance test in this study was 74.2%, and the kappa statistic’s 0.46. In conclusion, the results of the oral glucose tolerance test were reproducible in only 74.2% of pregnant women in this study. This highlights that a single oral glucose tolerance test for the diagnosis of gestational diabetes mellitus should be interpreted with caution. |
| first_indexed | 2024-12-16T08:28:27Z |
| format | Article |
| id | doaj.art-e99a1c5530bf4162b604467eb21da483 |
| institution | Directory Open Access Journal |
| issn | 1756-0500 |
| language | English |
| last_indexed | 2024-12-16T08:28:27Z |
| publishDate | 2017-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Research Notes |
| spelling | doaj.art-e99a1c5530bf4162b604467eb21da4832022-12-21T22:37:56ZengBMCBMC Research Notes1756-05002017-11-011011610.1186/s13104-017-2944-7Reproducibility of the 75 g oral glucose tolerance test for the diagnosis of gestational diabetes mellitus in a sub-Saharan African populationYvonne Nangeh Munang0Jean Jacques Noubiap1Celestin Danwang2Julius Dohbit Sama3Marcel Azabji-Kenfack4Jean Claude Mbanya5Eugene Sobngwi6Department of Internal Medicine and Specialties, Faculty of Medicine and Biomedical Sciences, University of Yaoundé IDepartment of Medicine, Groote Schuur Hospital and University of Cape TownDepartment of Surgery and Specialties, Faculty of Medicine and Biomedical Sciences, University of Yaoundé IDepartment of Obstetrics and Gynecology, Faculty of Medicine and Biomedical Sciences, University of Yaoundé IDepartment of Physiology, Faculty of Medicine and Biomedical Sciences, University of Yaoundé IDepartment of Internal Medicine and Specialties, Faculty of Medicine and Biomedical Sciences, University of Yaoundé IDepartment of Internal Medicine and Specialties, Faculty of Medicine and Biomedical Sciences, University of Yaoundé IAbstract Objective To evaluate the reproducibility of the 75 g oral glucose tolerance test and factors associated with non-reproducible results in Cameroonian pregnant women. Results Twenty-seven of the 84 participants (32.1%) who did the first oral glucose tolerance test were diagnosed with gestational diabetes mellitus. There was no difference between the means of the glycaemic responses at T0 (p = 0.64), T30 (p = 0.08), T60 (p = 0.86), T90 (p = 0.51), and T120 (p = 0.34) between the two oral glucose tolerance test. Age (p = 0.001) and BMI (p = 0.001) were significantly associated with non-reproducible results. The reproducibility of the oral glucose tolerance test in this study was 74.2%, and the kappa statistic’s 0.46. In conclusion, the results of the oral glucose tolerance test were reproducible in only 74.2% of pregnant women in this study. This highlights that a single oral glucose tolerance test for the diagnosis of gestational diabetes mellitus should be interpreted with caution.http://link.springer.com/article/10.1186/s13104-017-2944-7Gestational diabetesOral glucose tolerance testReproducibilityCameroonAfrica |
| spellingShingle | Yvonne Nangeh Munang Jean Jacques Noubiap Celestin Danwang Julius Dohbit Sama Marcel Azabji-Kenfack Jean Claude Mbanya Eugene Sobngwi Reproducibility of the 75 g oral glucose tolerance test for the diagnosis of gestational diabetes mellitus in a sub-Saharan African population BMC Research Notes Gestational diabetes Oral glucose tolerance test Reproducibility Cameroon Africa |
| title | Reproducibility of the 75 g oral glucose tolerance test for the diagnosis of gestational diabetes mellitus in a sub-Saharan African population |
| title_full | Reproducibility of the 75 g oral glucose tolerance test for the diagnosis of gestational diabetes mellitus in a sub-Saharan African population |
| title_fullStr | Reproducibility of the 75 g oral glucose tolerance test for the diagnosis of gestational diabetes mellitus in a sub-Saharan African population |
| title_full_unstemmed | Reproducibility of the 75 g oral glucose tolerance test for the diagnosis of gestational diabetes mellitus in a sub-Saharan African population |
| title_short | Reproducibility of the 75 g oral glucose tolerance test for the diagnosis of gestational diabetes mellitus in a sub-Saharan African population |
| title_sort | reproducibility of the 75 g oral glucose tolerance test for the diagnosis of gestational diabetes mellitus in a sub saharan african population |
| topic | Gestational diabetes Oral glucose tolerance test Reproducibility Cameroon Africa |
| url | http://link.springer.com/article/10.1186/s13104-017-2944-7 |
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