A Solid Ultra Fine Self-Nanoemulsifying Drug Delivery System (S-SNEDDS) of Deferasirox for Improved Solubility: Optimization, Characterization, and In Vitro Cytotoxicity Studies

A Solid Ultra Fine Self-Nanoemulsifying Drug Delivery System (S-SNEDDS) of Deferasirox for Improved Solubility: Optimization, Characterization, and In Vitro Cytotoxicity Studies

The research work was designed to develop a solid self-nanoemulsifying drug delivery system (S-SNEDDS) of deferasirox (DFX). According to the solubility studies of DFX in different components, Peceol, Kolliphor EL, and Transcutol were selected as excipients. Pseudo-ternary phase diagrams were constr...

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Bibliographic Details
Main Authors: Alaa Alghananim, Yıldız Özalp, Burcu Mesut, Nedime Serakinci, Yıldız Özsoy, Sevgi Güngör
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Pharmaceuticals
Subjects:
deferasirox
SNEDDS
solid SNEDDS
solid carriers
enhancement solubility
oral delivery
Online Access:https://www.mdpi.com/1424-8247/13/8/162

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