Melanopsin as a sleep modulator: circadian gating of the direct effects of light on sleep and altered sleep homeostasis in Opn4(-/-) mice.

Melanopsin as a sleep modulator: circadian gating of the direct effects of light on sleep and altered sleep homeostasis in Opn4(-/-) mice.

Light influences sleep and alertness either indirectly through a well-characterized circadian pathway or directly through yet poorly understood mechanisms. Melanopsin (Opn4) is a retinal photopigment crucial for conveying nonvisual light information to the brain. Through extensive characterization o...

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Bibliographic Details
Main Authors: Jessica W Tsai, Jens Hannibal, Grace Hagiwara, Damien Colas, Elisabeth Ruppert, Norman F Ruby, H Craig Heller, Paul Franken, Patrice Bourgin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19513122/?tool=EBI

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