Nanostructured lipid carriers containing benznidazole: physicochemical, biopharmaceutical and cellular in vitro studies

Nanostructured lipid carriers containing benznidazole: physicochemical, biopharmaceutical and cellular in vitro studies

Chagas disease is a neglected endemic disease prevalent in Latin American countries, affecting around 8 million people. The first-line treatment, benznidazole (BNZ), is effective in the acute stage of the disease but has limited efficacy in the chronic stage, possibly because current treatment regim...

Full description

Bibliographic Details
Main Authors: Giuliana Muraca, María Esperanza Ruiz, Rocío C. Gambaro, Sebastián Scioli-Montoto, María Laura Sbaraglini, Gisel Padula, José Sebastián Cisneros, Cecilia Yamil Chain, Vera A. Álvarez, Cristián Huck-Iriart, Guillermo R. Castro, María Belén Piñero, Matias Ildebrando Marchetto, Catalina Alba Soto, Germán A. Islan, Alan Talevi
Format: Article
Language:English
Published: Beilstein-Institut 2023-07-01
Series:Beilstein Journal of Nanotechnology
Subjects:
benznidazole
biopharmaceutical study
chagas disease
nanoparticles
nanostructured lipid carriers
physicochemical characterization
trypanosoma cruzi
Online Access:https://doi.org/10.3762/bjnano.14.66

Internet

https://doi.org/10.3762/bjnano.14.66

Similar Items