What Should Be the Prostate Specific Antigen Threshold for Prostate Biopsy?
Aim: There is still uncertainty today regarding the prostate specific antigen (PSA) threshold for prostate biopsy. From this point of view, we aimed to investigate the PSA threshold for prostate biopsy in this study. Methods: We retrospectively evaluated medical records of 375 patients, who underwe...
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2017-06-01
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| Series: | Haseki Tıp Bülteni |
| Subjects: | |
| Online Access: | http://www.hasekidergisi.com/article_15013/What-Should-Be-The-Prostate-Specific-Antigen-Threshold-For-Prostate-Biopsy |
| _version_ | 1797909516118917120 |
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| author | Hasan Deliktaş Hayrettin Şahin |
| author_facet | Hasan Deliktaş Hayrettin Şahin |
| author_sort | Hasan Deliktaş |
| collection | DOAJ |
| description | Aim: There is still uncertainty today regarding the prostate specific antigen (PSA) threshold for prostate biopsy. From this point of view, we aimed to investigate the PSA threshold for prostate biopsy in this study.
Methods: We retrospectively evaluated medical records of 375 patients, who underwent 12-16-core transrectal ultrasound-guided prostate biopsy between September 2012 and November 2015. The patients were divided into three groups according to the PSA values: group 1: 2.5-4ng/mL, group 2: 4.1-10 ng/mL and group 3: >10 ng/mL. Age, prostate volume, prostate cancer detection rate, Gleason score, the average core length and the core length obtained per cc of prostate volume were compared between the groups.
Results: The mean age of the patients was 64.39±7.62 years and the mean cancer detection rate was 26.7%, namely 11.5% (3/26), 17.4% (43/247) and 52.9% (54/102) in the groups 1, 2 and 3, respectively. Prostate cancer was not detected in any patient with a PSA value of <3.6 ng/mL (n=13).
Conclusion: Since prostate cancer was not detected in any patient with a PSA value of <3.6 ng/mL in our study, we suggest higher PSA threshold values in order to reduce unnecessary prostate biopsy procedures. |
| first_indexed | 2024-04-10T11:09:36Z |
| format | Article |
| id | doaj.art-e9a4ac9adb5a401883d6a00c3327595f |
| institution | Directory Open Access Journal |
| issn | 1302-0072 2147-2688 |
| language | English |
| last_indexed | 2024-04-10T11:09:36Z |
| publishDate | 2017-06-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Haseki Tıp Bülteni |
| spelling | doaj.art-e9a4ac9adb5a401883d6a00c3327595f2023-02-15T16:19:14ZengGalenos YayineviHaseki Tıp Bülteni1302-00722147-26882017-06-0155214615010.4274/haseki.3212What Should Be the Prostate Specific Antigen Threshold for Prostate Biopsy?Hasan Deliktaş0Hayrettin Şahin1Muğla Sıtkı Kocman University Faculty of Medicine, Department of Urology, Muğla, TurkeyMuğla Sıtkı Kocman University Faculty of Medicine, Department of Urology, Muğla, TurkeyAim: There is still uncertainty today regarding the prostate specific antigen (PSA) threshold for prostate biopsy. From this point of view, we aimed to investigate the PSA threshold for prostate biopsy in this study. Methods: We retrospectively evaluated medical records of 375 patients, who underwent 12-16-core transrectal ultrasound-guided prostate biopsy between September 2012 and November 2015. The patients were divided into three groups according to the PSA values: group 1: 2.5-4ng/mL, group 2: 4.1-10 ng/mL and group 3: >10 ng/mL. Age, prostate volume, prostate cancer detection rate, Gleason score, the average core length and the core length obtained per cc of prostate volume were compared between the groups. Results: The mean age of the patients was 64.39±7.62 years and the mean cancer detection rate was 26.7%, namely 11.5% (3/26), 17.4% (43/247) and 52.9% (54/102) in the groups 1, 2 and 3, respectively. Prostate cancer was not detected in any patient with a PSA value of <3.6 ng/mL (n=13). Conclusion: Since prostate cancer was not detected in any patient with a PSA value of <3.6 ng/mL in our study, we suggest higher PSA threshold values in order to reduce unnecessary prostate biopsy procedures.http://www.hasekidergisi.com/article_15013/What-Should-Be-The-Prostate-Specific-Antigen-Threshold-For-Prostate-BiopsyProstate cancerprostate specific antigen thresholdprostate biopsy |
| spellingShingle | Hasan Deliktaş Hayrettin Şahin What Should Be the Prostate Specific Antigen Threshold for Prostate Biopsy? Haseki Tıp Bülteni Prostate cancer prostate specific antigen threshold prostate biopsy |
| title | What Should Be the Prostate Specific Antigen Threshold for Prostate Biopsy? |
| title_full | What Should Be the Prostate Specific Antigen Threshold for Prostate Biopsy? |
| title_fullStr | What Should Be the Prostate Specific Antigen Threshold for Prostate Biopsy? |
| title_full_unstemmed | What Should Be the Prostate Specific Antigen Threshold for Prostate Biopsy? |
| title_short | What Should Be the Prostate Specific Antigen Threshold for Prostate Biopsy? |
| title_sort | what should be the prostate specific antigen threshold for prostate biopsy |
| topic | Prostate cancer prostate specific antigen threshold prostate biopsy |
| url | http://www.hasekidergisi.com/article_15013/What-Should-Be-The-Prostate-Specific-Antigen-Threshold-For-Prostate-Biopsy |
| work_keys_str_mv | AT hasandeliktas whatshouldbetheprostatespecificantigenthresholdforprostatebiopsy AT hayrettinsahin whatshouldbetheprostatespecificantigenthresholdforprostatebiopsy |