Chronic Thromboembolic Pulmonary Hypertension Due to Popliteal Vein Aneurysm
Masakazu Tsubono,1,2 Kazuhiro Shimizu,2 Shuji Sato,2 Takuro Ito,2 Takanori Ikeda1 1Department of Internal Medicine, Toho University Omori Medical Center, Tokyo, Japan; 2Department of Internal Medicine, Toho University Sakura Medical Center, Chiba, JapanCorrespondence: Kazuhiro ShimizuDepartment of I...
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Dove Medical Press
2021-02-01
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| Series: | International Medical Case Reports Journal |
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| Online Access: | https://www.dovepress.com/chronic-thromboembolic-pulmonary-hypertension-due-to-popliteal-vein-an-peer-reviewed-article-IMCRJ |
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| author | Tsubono M Shimizu K Sato S Ito T Ikeda T |
| author_facet | Tsubono M Shimizu K Sato S Ito T Ikeda T |
| author_sort | Tsubono M |
| collection | DOAJ |
| description | Masakazu Tsubono,1,2 Kazuhiro Shimizu,2 Shuji Sato,2 Takuro Ito,2 Takanori Ikeda1 1Department of Internal Medicine, Toho University Omori Medical Center, Tokyo, Japan; 2Department of Internal Medicine, Toho University Sakura Medical Center, Chiba, JapanCorrespondence: Kazuhiro ShimizuDepartment of Internal Medicine, Sakura Medical Center, School of Medicine, Toho University, 561-4 Shimoshizu, Sakura City, Chiba, 285-8741, JapanTel +81-43-462-8811Fax +81-43-462-8820Email k432@sakura.med.toho-u.ac.jpBackground: Venous thromboembolism (VTE) may present acutely as pulmonary embolism (PE), and its late complications include chronic thromboembolic pulmonary hypertension (CTEPH). PEs may arise from thrombi originating in a venous aneurysm, in rare cases of the popliteal vein.Case Presentation: A 77-year-old woman was referred to our hospital due to respiratory distress. Computed tomography revealed pulmonary thrombi and a thrombus in a popliteal vein aneurysm (PVA); PE was diagnosed. After 3 months of anticoagulant therapy (rivaroxaban), her pulmonary hypertension showed little improvement. She underwent perfusion scintigraphy, which showed multiple perfusion defects, and Swan–Ganz catheterization. Mean pulmonary artery pressure was 26 mmHg. Pulmonary angiography revealed organized distal thrombi. Based on these findings, we diagnosed CTEPH due to recurrent formation of thrombi in the PVA.Conclusion: Asymptomatic PVA can lead silently to PE and CTEPH. The possibility of asymptomatic recurrent VTE should be considered in patients with pulmonary hypertension and PVA.Keywords: chronic thromboembolic pulmonary hypertension, popliteal vein aneurysm, pulmonary embolism, pulmonary hypertension, venous thromboembolism |
| first_indexed | 2024-12-20T13:24:18Z |
| format | Article |
| id | doaj.art-e9a5fce620344c89b2605ac02a1b0a59 |
| institution | Directory Open Access Journal |
| issn | 1179-142X |
| language | English |
| last_indexed | 2024-12-20T13:24:18Z |
| publishDate | 2021-02-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Medical Case Reports Journal |
| spelling | doaj.art-e9a5fce620344c89b2605ac02a1b0a592022-12-21T19:39:20ZengDove Medical PressInternational Medical Case Reports Journal1179-142X2021-02-01Volume 1410110662239Chronic Thromboembolic Pulmonary Hypertension Due to Popliteal Vein AneurysmTsubono MShimizu KSato SIto TIkeda TMasakazu Tsubono,1,2 Kazuhiro Shimizu,2 Shuji Sato,2 Takuro Ito,2 Takanori Ikeda1 1Department of Internal Medicine, Toho University Omori Medical Center, Tokyo, Japan; 2Department of Internal Medicine, Toho University Sakura Medical Center, Chiba, JapanCorrespondence: Kazuhiro ShimizuDepartment of Internal Medicine, Sakura Medical Center, School of Medicine, Toho University, 561-4 Shimoshizu, Sakura City, Chiba, 285-8741, JapanTel +81-43-462-8811Fax +81-43-462-8820Email k432@sakura.med.toho-u.ac.jpBackground: Venous thromboembolism (VTE) may present acutely as pulmonary embolism (PE), and its late complications include chronic thromboembolic pulmonary hypertension (CTEPH). PEs may arise from thrombi originating in a venous aneurysm, in rare cases of the popliteal vein.Case Presentation: A 77-year-old woman was referred to our hospital due to respiratory distress. Computed tomography revealed pulmonary thrombi and a thrombus in a popliteal vein aneurysm (PVA); PE was diagnosed. After 3 months of anticoagulant therapy (rivaroxaban), her pulmonary hypertension showed little improvement. She underwent perfusion scintigraphy, which showed multiple perfusion defects, and Swan–Ganz catheterization. Mean pulmonary artery pressure was 26 mmHg. Pulmonary angiography revealed organized distal thrombi. Based on these findings, we diagnosed CTEPH due to recurrent formation of thrombi in the PVA.Conclusion: Asymptomatic PVA can lead silently to PE and CTEPH. The possibility of asymptomatic recurrent VTE should be considered in patients with pulmonary hypertension and PVA.Keywords: chronic thromboembolic pulmonary hypertension, popliteal vein aneurysm, pulmonary embolism, pulmonary hypertension, venous thromboembolismhttps://www.dovepress.com/chronic-thromboembolic-pulmonary-hypertension-due-to-popliteal-vein-an-peer-reviewed-article-IMCRJchronic thromboembolic pulmonary hypertensionpopliteal vein aneurysmpulmonary embolismpulmonary hypertensionvenous thromboembolism |
| spellingShingle | Tsubono M Shimizu K Sato S Ito T Ikeda T Chronic Thromboembolic Pulmonary Hypertension Due to Popliteal Vein Aneurysm International Medical Case Reports Journal chronic thromboembolic pulmonary hypertension popliteal vein aneurysm pulmonary embolism pulmonary hypertension venous thromboembolism |
| title | Chronic Thromboembolic Pulmonary Hypertension Due to Popliteal Vein Aneurysm |
| title_full | Chronic Thromboembolic Pulmonary Hypertension Due to Popliteal Vein Aneurysm |
| title_fullStr | Chronic Thromboembolic Pulmonary Hypertension Due to Popliteal Vein Aneurysm |
| title_full_unstemmed | Chronic Thromboembolic Pulmonary Hypertension Due to Popliteal Vein Aneurysm |
| title_short | Chronic Thromboembolic Pulmonary Hypertension Due to Popliteal Vein Aneurysm |
| title_sort | chronic thromboembolic pulmonary hypertension due to popliteal vein aneurysm |
| topic | chronic thromboembolic pulmonary hypertension popliteal vein aneurysm pulmonary embolism pulmonary hypertension venous thromboembolism |
| url | https://www.dovepress.com/chronic-thromboembolic-pulmonary-hypertension-due-to-popliteal-vein-an-peer-reviewed-article-IMCRJ |
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