MiRNA-29b and miRNA-497 Modulate the Expression of Carboxypeptidase X Member 2, a Candidate Gene Associated with Left Ventricular Hypertrophy

MiRNA-29b and miRNA-497 Modulate the Expression of Carboxypeptidase X Member 2, a Candidate Gene Associated with Left Ventricular Hypertrophy

Left ventricular hypertrophy (LVH) is a major risk factor for adverse cardiovascular events. Recently, a novel candidate gene encoding the carboxypeptidase X member 2 (CPXM2) was found to be associated with hypertension-induced LVH. CPXM2 belongs to the M14 family of metallocarboxypeptidases, yet it...

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Bibliographic Details
Main Authors: Jana Subrova, Karen Böhme, Allan Gillespie, Miriam Orphal, Claudia Plum, Reinhold Kreutz, Andreas Eisenreich
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:International Journal of Molecular Sciences
Subjects:
carboxypeptidase X member 2
microRNA
posttranscriptional
gene expression
left ventricular hypertrophy
Online Access:https://www.mdpi.com/1422-0067/23/4/2263

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