Environmentally induced ribosomal DNA (rDNA) instability in human cells and populations exposed to hexavalent chromium [Cr (VI)]

Environmentally induced ribosomal DNA (rDNA) instability in human cells and populations exposed to hexavalent chromium [Cr (VI)]

Hexavalent Chromium [Cr (VI)] is an established toxicant, carcinogen, and a significant source of public health concern. The multicopy ribosomal DNA (rDNA) array is mechanistically linked to aging and cancer, is the most evolutionarily conserved segment of the human genome, and gives origin to nucle...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Jianlin Lou, Shoukai Yu, Lingfang Feng, Xinnian Guo, Meng Wang, Alan T. Branco, Tao Li, Bernardo Lemos
التنسيق: مقال
اللغة:English
منشور في: Elsevier 2021-08-01
سلاسل:Environment International
الموضوعات:
Chromium
Ribosome
rDNA
Nucleolus
Copy number
الوصول للمادة أونلاين:http://www.sciencedirect.com/science/article/pii/S0160412021001501

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