Environmentally induced ribosomal DNA (rDNA) instability in human cells and populations exposed to hexavalent chromium [Cr (VI)]
Hexavalent Chromium [Cr (VI)] is an established toxicant, carcinogen, and a significant source of public health concern. The multicopy ribosomal DNA (rDNA) array is mechanistically linked to aging and cancer, is the most evolutionarily conserved segment of the human genome, and gives origin to nucle...
Main Authors: | Jianlin Lou, Shoukai Yu, Lingfang Feng, Xinnian Guo, Meng Wang, Alan T. Branco, Tao Li, Bernardo Lemos |
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Format: | Article |
Sprog: | English |
Udgivet: |
Elsevier
2021-08-01
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Serier: | Environment International |
Fag: | |
Online adgang: | http://www.sciencedirect.com/science/article/pii/S0160412021001501 |
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