Environmentally induced ribosomal DNA (rDNA) instability in human cells and populations exposed to hexavalent chromium [Cr (VI)]

Environmentally induced ribosomal DNA (rDNA) instability in human cells and populations exposed to hexavalent chromium [Cr (VI)]

Hexavalent Chromium [Cr (VI)] is an established toxicant, carcinogen, and a significant source of public health concern. The multicopy ribosomal DNA (rDNA) array is mechanistically linked to aging and cancer, is the most evolutionarily conserved segment of the human genome, and gives origin to nucle...

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Bibliografiska uppgifter
Huvudupphovsmän: Jianlin Lou, Shoukai Yu, Lingfang Feng, Xinnian Guo, Meng Wang, Alan T. Branco, Tao Li, Bernardo Lemos
Materialtyp: Artikel
Språk:English
Publicerad: Elsevier 2021-08-01
Serie:Environment International
Ämnen:
Chromium
Ribosome
rDNA
Nucleolus
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Länkar:http://www.sciencedirect.com/science/article/pii/S0160412021001501

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