Complications of Nonpermanent Facial Fillers: A Systematic Review
Background:. A variety of complications after injection of nonpermanent fillers for facial rejuvenation have been reported so far. However, to date, the overall complication rate is still a matter of debate. The aim of this study was to perform a systematic review of literature to assess the type an...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer
2021-10-01
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| Series: | Plastic and Reconstructive Surgery, Global Open |
| Online Access: | http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000003851 |
| _version_ | 1819030841775357952 |
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| author | Carlo M. Oranges, MD, PhD Davide Brucato, MD Dirk J. Schaefer, MD Daniel F. Kalbermatten, MD, PhD Yves Harder, MD |
| author_facet | Carlo M. Oranges, MD, PhD Davide Brucato, MD Dirk J. Schaefer, MD Daniel F. Kalbermatten, MD, PhD Yves Harder, MD |
| author_sort | Carlo M. Oranges, MD, PhD |
| collection | DOAJ |
| description | Background:. A variety of complications after injection of nonpermanent fillers for facial rejuvenation have been reported so far. However, to date, the overall complication rate is still a matter of debate. The aim of this study was to perform a systematic review of literature to assess the type and severity of associated complications following injections in different anatomical regions of the face.
Methods:. The entire PubMed/Medline database was screened to identify case reports and clinical studies describing complications that have occurred after injection of nonpermanent fillers in the face. These complications have been reviewed and analyzed according to their occurrence in different anatomical regions of the face.
Results:. Forty-six articles including a total of 164 patients reported on a total of 436 complications during the time period between January 2003 and February 2020. The majority of the complications were reported after injections to the nose and the nasolabial fold (n = 230), the forehead and the eyebrows (n = 53), and the glabellar region (n = 36). Out of 436 complications, 163 have been classified as severe or permanent including skin necrosis (n = 46), loss of vision (n = 35), or encephalitis (n = 1), whereas 273 complications were classified as mild or transient, such as local edema (n = 74), skin erythema (n = 69), and filler migration (n = 2). The most severe complications were observed in treatments of nose, glabella, and forehead.
Conclusions:. Nonpermanent facial fillers are associated with rare but potentially severe complications. Severity and impact of complications depend on the anatomical region of the face and eventually require profound knowledge of facial anatomy. |
| first_indexed | 2024-12-21T06:36:34Z |
| format | Article |
| id | doaj.art-e9abfcb8947d41d4a3fbb86bf95c775c |
| institution | Directory Open Access Journal |
| issn | 2169-7574 |
| language | English |
| last_indexed | 2024-12-21T06:36:34Z |
| publishDate | 2021-10-01 |
| publisher | Wolters Kluwer |
| record_format | Article |
| series | Plastic and Reconstructive Surgery, Global Open |
| spelling | doaj.art-e9abfcb8947d41d4a3fbb86bf95c775c2022-12-21T19:12:52ZengWolters KluwerPlastic and Reconstructive Surgery, Global Open2169-75742021-10-01910e385110.1097/GOX.0000000000003851202110000-00038Complications of Nonpermanent Facial Fillers: A Systematic ReviewCarlo M. Oranges, MD, PhD0Davide Brucato, MD1Dirk J. Schaefer, MD2Daniel F. Kalbermatten, MD, PhD3Yves Harder, MD4From the * Department of Plastic, Reconstructive and Aesthetic Surgery, Geneva University Hospitals (HUG), University of Geneva, Geneva, Switzerland† Department of Plastic, Reconstructive and Aesthetic Surgery, Ospedale Regionale di Lugano, Ente Ospedaliero Cantonale (EOC), Lugano, Switzerland§ Department of Plastic, Reconstructive, Aesthetic, and Hand Surgery, Basel University Hospital, Basel, Switzerland.From the * Department of Plastic, Reconstructive and Aesthetic Surgery, Geneva University Hospitals (HUG), University of Geneva, Geneva, Switzerland† Department of Plastic, Reconstructive and Aesthetic Surgery, Ospedale Regionale di Lugano, Ente Ospedaliero Cantonale (EOC), Lugano, SwitzerlandBackground:. A variety of complications after injection of nonpermanent fillers for facial rejuvenation have been reported so far. However, to date, the overall complication rate is still a matter of debate. The aim of this study was to perform a systematic review of literature to assess the type and severity of associated complications following injections in different anatomical regions of the face. Methods:. The entire PubMed/Medline database was screened to identify case reports and clinical studies describing complications that have occurred after injection of nonpermanent fillers in the face. These complications have been reviewed and analyzed according to their occurrence in different anatomical regions of the face. Results:. Forty-six articles including a total of 164 patients reported on a total of 436 complications during the time period between January 2003 and February 2020. The majority of the complications were reported after injections to the nose and the nasolabial fold (n = 230), the forehead and the eyebrows (n = 53), and the glabellar region (n = 36). Out of 436 complications, 163 have been classified as severe or permanent including skin necrosis (n = 46), loss of vision (n = 35), or encephalitis (n = 1), whereas 273 complications were classified as mild or transient, such as local edema (n = 74), skin erythema (n = 69), and filler migration (n = 2). The most severe complications were observed in treatments of nose, glabella, and forehead. Conclusions:. Nonpermanent facial fillers are associated with rare but potentially severe complications. Severity and impact of complications depend on the anatomical region of the face and eventually require profound knowledge of facial anatomy.http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000003851 |
| spellingShingle | Carlo M. Oranges, MD, PhD Davide Brucato, MD Dirk J. Schaefer, MD Daniel F. Kalbermatten, MD, PhD Yves Harder, MD Complications of Nonpermanent Facial Fillers: A Systematic Review Plastic and Reconstructive Surgery, Global Open |
| title | Complications of Nonpermanent Facial Fillers: A Systematic Review |
| title_full | Complications of Nonpermanent Facial Fillers: A Systematic Review |
| title_fullStr | Complications of Nonpermanent Facial Fillers: A Systematic Review |
| title_full_unstemmed | Complications of Nonpermanent Facial Fillers: A Systematic Review |
| title_short | Complications of Nonpermanent Facial Fillers: A Systematic Review |
| title_sort | complications of nonpermanent facial fillers a systematic review |
| url | http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000003851 |
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