Racial and ethnic disparities in diagnosis, management and outcomes of aortic stenosis in the Medicare population

<h4>Importance</h4> Aortic stenosis (AS) is one of the most common heart valve conditions and its incidence and prevalence increases with age. With the introduction of transcatheter aortic valve replacement (TAVR), racial and ethnic disparities in AS diagnosis, treatment and outcomes is...

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Main Authors: Yunus Ahmed, Pieter A. J. van Bakel, Hechuan Hou, Devraj Sukul, Donald S. Likosky, Joost A. van Herwaarden, Daphne C. Watkins, Gorav Ailawadi, Himanshu J. Patel, Michael P. Thompson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085041/?tool=EBI
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author Yunus Ahmed
Pieter A. J. van Bakel
Hechuan Hou
Devraj Sukul
Donald S. Likosky
Joost A. van Herwaarden
Daphne C. Watkins
Gorav Ailawadi
Himanshu J. Patel
Michael P. Thompson
author_facet Yunus Ahmed
Pieter A. J. van Bakel
Hechuan Hou
Devraj Sukul
Donald S. Likosky
Joost A. van Herwaarden
Daphne C. Watkins
Gorav Ailawadi
Himanshu J. Patel
Michael P. Thompson
author_sort Yunus Ahmed
collection DOAJ
description <h4>Importance</h4> Aortic stenosis (AS) is one of the most common heart valve conditions and its incidence and prevalence increases with age. With the introduction of transcatheter aortic valve replacement (TAVR), racial and ethnic disparities in AS diagnosis, treatment and outcomes is poorly understood. <h4>Objective</h4> In this study we assessed racial and ethnic disparities in AS diagnosis, treatment, and outcomes among Medicare beneficiaries. <h4>Design</h4> We conducted a population-based cohort study of inpatient, outpatient, and professional claims from a 20% sample of Medicare beneficiaries <h4>Main outcomes and measures</h4> Incidence and Prevalence was determined among Medicare Beneficiaries. Outcomes in this study included management; the number of (non)-interventional cardiology and cardiothoracic surgery evaluation and management (E&M) visits, and number of transthoracic echocardiograms (TTE) performed. Treatment, which was defined as Surgical Aortic Valve Replacement and Transthoracic Aortic Valve Replacement. And outcomes described as All-cause Hospitalizations, Heart Failure Hospitalization and 1-year mortality. <h4>Results</h4> A total of 1,513,455 Medicare beneficiaries were diagnosed with AS (91.3% White, 4.5% Black, 1.1% Hispanic, 3.1% Asian and North American Native) between 2010 and 2018. Annual prevalence of AS diagnosis was lower for racial and ethnic minorities compared with White patients, with adjusted rate ratios of 0.66 (95% CI 0.65 to 0.68) for Black patients, 0.67 (95% CI 0.64 to 0.70) for Hispanic patients and 0.75 (95% CI 0.73 to 0.77) for Asian and North American Native patients as recent as 2018. After adjusting for age, sex and comorbidities, cardiothoracic surgery E&M visits and treatment rates were significantly lower for Black, Hispanic and Asian and North American Native patients compared with White patients. All-cause hospitalization rate was higher for Black and Hispanic patients compared with White patient. 1-year mortality was higher for Black patients, while Hispanic and Asian and North American Native patients had lower 1-year mortality compared with White patients. <h4>Conclusions and relevance</h4> We demonstrated significant racial and ethnic disparities in the diagnosis, management and outcomes of AS. The factors driving the persistence of these disparities in AS care need to be elucidated to develop an equitable health care system.
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spelling doaj.art-e9b2917da15343af9a880ddb6844e8122023-04-14T05:31:43ZengPublic Library of Science (PLoS)PLoS ONE1932-62032023-01-01184Racial and ethnic disparities in diagnosis, management and outcomes of aortic stenosis in the Medicare populationYunus AhmedPieter A. J. van BakelHechuan HouDevraj SukulDonald S. LikoskyJoost A. van HerwaardenDaphne C. WatkinsGorav AilawadiHimanshu J. PatelMichael P. Thompson<h4>Importance</h4> Aortic stenosis (AS) is one of the most common heart valve conditions and its incidence and prevalence increases with age. With the introduction of transcatheter aortic valve replacement (TAVR), racial and ethnic disparities in AS diagnosis, treatment and outcomes is poorly understood. <h4>Objective</h4> In this study we assessed racial and ethnic disparities in AS diagnosis, treatment, and outcomes among Medicare beneficiaries. <h4>Design</h4> We conducted a population-based cohort study of inpatient, outpatient, and professional claims from a 20% sample of Medicare beneficiaries <h4>Main outcomes and measures</h4> Incidence and Prevalence was determined among Medicare Beneficiaries. Outcomes in this study included management; the number of (non)-interventional cardiology and cardiothoracic surgery evaluation and management (E&M) visits, and number of transthoracic echocardiograms (TTE) performed. Treatment, which was defined as Surgical Aortic Valve Replacement and Transthoracic Aortic Valve Replacement. And outcomes described as All-cause Hospitalizations, Heart Failure Hospitalization and 1-year mortality. <h4>Results</h4> A total of 1,513,455 Medicare beneficiaries were diagnosed with AS (91.3% White, 4.5% Black, 1.1% Hispanic, 3.1% Asian and North American Native) between 2010 and 2018. Annual prevalence of AS diagnosis was lower for racial and ethnic minorities compared with White patients, with adjusted rate ratios of 0.66 (95% CI 0.65 to 0.68) for Black patients, 0.67 (95% CI 0.64 to 0.70) for Hispanic patients and 0.75 (95% CI 0.73 to 0.77) for Asian and North American Native patients as recent as 2018. After adjusting for age, sex and comorbidities, cardiothoracic surgery E&M visits and treatment rates were significantly lower for Black, Hispanic and Asian and North American Native patients compared with White patients. All-cause hospitalization rate was higher for Black and Hispanic patients compared with White patient. 1-year mortality was higher for Black patients, while Hispanic and Asian and North American Native patients had lower 1-year mortality compared with White patients. <h4>Conclusions and relevance</h4> We demonstrated significant racial and ethnic disparities in the diagnosis, management and outcomes of AS. The factors driving the persistence of these disparities in AS care need to be elucidated to develop an equitable health care system.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085041/?tool=EBI
spellingShingle Yunus Ahmed
Pieter A. J. van Bakel
Hechuan Hou
Devraj Sukul
Donald S. Likosky
Joost A. van Herwaarden
Daphne C. Watkins
Gorav Ailawadi
Himanshu J. Patel
Michael P. Thompson
Racial and ethnic disparities in diagnosis, management and outcomes of aortic stenosis in the Medicare population
PLoS ONE
title Racial and ethnic disparities in diagnosis, management and outcomes of aortic stenosis in the Medicare population
title_full Racial and ethnic disparities in diagnosis, management and outcomes of aortic stenosis in the Medicare population
title_fullStr Racial and ethnic disparities in diagnosis, management and outcomes of aortic stenosis in the Medicare population
title_full_unstemmed Racial and ethnic disparities in diagnosis, management and outcomes of aortic stenosis in the Medicare population
title_short Racial and ethnic disparities in diagnosis, management and outcomes of aortic stenosis in the Medicare population
title_sort racial and ethnic disparities in diagnosis management and outcomes of aortic stenosis in the medicare population
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085041/?tool=EBI
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