Harnessing the medicinal properties of Cussonia barteri Seem. (Araliaceae) in drug development. A review
Cussonia barteri Seem (Araliaceae) is a deciduous tree growing in savannah of Africa. Ethnomedicinally, it is used in Africa as an analgesic, anti-malarial, anti-inflammatory, anti-anaemic, anti-diarhoea, anti-poison, ani-pyschotic and anti-epileptic agent. This review provides a brief summary on th...
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| Format: | Article |
| Language: | English |
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Polish Ministry of Science and Higher Education
2018-09-01
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| Series: | Herba Polonica |
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| Online Access: | https://doi.org/10.2478/hepo-2018-0018 |
| _version_ | 1797705223829979136 |
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| author | Igbe Ighodaro Edosuyi Osaze Okhuarobo Agbonlahor |
| author_facet | Igbe Ighodaro Edosuyi Osaze Okhuarobo Agbonlahor |
| author_sort | Igbe Ighodaro |
| collection | DOAJ |
| description | Cussonia barteri Seem (Araliaceae) is a deciduous tree growing in savannah of Africa. Ethnomedicinally, it is used in Africa as an analgesic, anti-malarial, anti-inflammatory, anti-anaemic, anti-diarhoea, anti-poison, ani-pyschotic and anti-epileptic agent. This review provides a brief summary on the phytochemical screenings, ethnomedicinal and pharmacological applications of various parts of C. barteri. Leaves, stem bark and seed of C. barteri have been shown to be rich in saponins, flavonoids, phenols, sugars and alkaloids. Some of these constituents have been isolated and elucidated from C. barteri. Several compounds isolated from plant include triterpenes, saponins, polyenyne and quinic esters. Phytochemical constituents are also partly responsible for biological activities of C. barteri. Extracts and components isolated from the plant have demonstrated neuropharmacological, anti-larvicidal, anti-microbial, anti-inflammatory and antioxidant activities. Overall, the insights provided by this review reinforce the potential of C. barteri for drug development and create the need for further scientific probe of constituents of the plant with the aim of developing novel drug candidates. |
| first_indexed | 2024-03-12T05:32:58Z |
| format | Article |
| id | doaj.art-e9b3b474604c4efcb6a0d20b2b841dd0 |
| institution | Directory Open Access Journal |
| issn | 2449-8343 |
| language | English |
| last_indexed | 2024-03-12T05:32:58Z |
| publishDate | 2018-09-01 |
| publisher | Polish Ministry of Science and Higher Education |
| record_format | Article |
| series | Herba Polonica |
| spelling | doaj.art-e9b3b474604c4efcb6a0d20b2b841dd02023-09-03T06:45:39ZengPolish Ministry of Science and Higher EducationHerba Polonica2449-83432018-09-01643506110.2478/hepo-2018-0018hepo-2018-0018Harnessing the medicinal properties of Cussonia barteri Seem. (Araliaceae) in drug development. A reviewIgbe Ighodaro0Edosuyi Osaze1Okhuarobo Agbonlahor2Department of Pharmacology and Toxicology, Faculty of Pharmacy, University of Benin, Benin City, NigeriaDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, University of Benin, Benin City, NigeriaDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, University of Benin, Benin City, NigeriaCussonia barteri Seem (Araliaceae) is a deciduous tree growing in savannah of Africa. Ethnomedicinally, it is used in Africa as an analgesic, anti-malarial, anti-inflammatory, anti-anaemic, anti-diarhoea, anti-poison, ani-pyschotic and anti-epileptic agent. This review provides a brief summary on the phytochemical screenings, ethnomedicinal and pharmacological applications of various parts of C. barteri. Leaves, stem bark and seed of C. barteri have been shown to be rich in saponins, flavonoids, phenols, sugars and alkaloids. Some of these constituents have been isolated and elucidated from C. barteri. Several compounds isolated from plant include triterpenes, saponins, polyenyne and quinic esters. Phytochemical constituents are also partly responsible for biological activities of C. barteri. Extracts and components isolated from the plant have demonstrated neuropharmacological, anti-larvicidal, anti-microbial, anti-inflammatory and antioxidant activities. Overall, the insights provided by this review reinforce the potential of C. barteri for drug development and create the need for further scientific probe of constituents of the plant with the aim of developing novel drug candidates.https://doi.org/10.2478/hepo-2018-0018cussonia barteriisolated compoundsphytochemical constituentsethnomedicine |
| spellingShingle | Igbe Ighodaro Edosuyi Osaze Okhuarobo Agbonlahor Harnessing the medicinal properties of Cussonia barteri Seem. (Araliaceae) in drug development. A review Herba Polonica cussonia barteri isolated compounds phytochemical constituents ethnomedicine |
| title | Harnessing the medicinal properties of Cussonia barteri Seem. (Araliaceae) in drug development. A review |
| title_full | Harnessing the medicinal properties of Cussonia barteri Seem. (Araliaceae) in drug development. A review |
| title_fullStr | Harnessing the medicinal properties of Cussonia barteri Seem. (Araliaceae) in drug development. A review |
| title_full_unstemmed | Harnessing the medicinal properties of Cussonia barteri Seem. (Araliaceae) in drug development. A review |
| title_short | Harnessing the medicinal properties of Cussonia barteri Seem. (Araliaceae) in drug development. A review |
| title_sort | harnessing the medicinal properties of cussonia barteri seem araliaceae in drug development a review |
| topic | cussonia barteri isolated compounds phytochemical constituents ethnomedicine |
| url | https://doi.org/10.2478/hepo-2018-0018 |
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