Neural stem cell-encoded temporal patterning delineates an early window of malignant susceptibility in Drosophila

Neural stem cell-encoded temporal patterning delineates an early window of malignant susceptibility in Drosophila

Pediatric neural tumors are often initiated during early development and can undergo very rapid transformation. However, the molecular basis of this early malignant susceptibility remains unknown. During Drosophila development, neural stem cells (NSCs) divide asymmetrically and generate intermediate...

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Bibliographic Details
Main Authors: Karine Narbonne-Reveau, Elodie Lanet, Caroline Dillard, Sophie Foppolo, Ching-Huan Chen, Hugues Parrinello, Stéphanie Rialle, Nicholas S Sokol, Cédric Maurange
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-06-01
Series:eLife
Subjects:
neuroblasts
neural stem cell
developmental origin of cancer
pediatric cancer
Online Access:https://elifesciences.org/articles/13463

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