Evaluation of Aerosol Electrospray Analysis of Metal-on-Metal Wear Particles from Simulated Total Joint Replacement

Wear is a common cause for aseptic loosening in artificial joints. The purpose of this study was to develop an automated diagnostical method for identification of the number and size distribution of wear debris. For this purpose, metal debris samples were extracted from a hip simulator and then anal...

Full description

Bibliographic Details
Main Authors: Gobert von Skrbensky, Karoline Mühlbacher, Emir Benca, Alexander Kolb, Reinhard Windhager, Georg Reischl, Georg Reinisch
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Sensors
Subjects:
Online Access:https://www.mdpi.com/1424-8220/19/17/3751
_version_ 1798039484735946752
author Gobert von Skrbensky
Karoline Mühlbacher
Emir Benca
Alexander Kolb
Reinhard Windhager
Georg Reischl
Georg Reinisch
author_facet Gobert von Skrbensky
Karoline Mühlbacher
Emir Benca
Alexander Kolb
Reinhard Windhager
Georg Reischl
Georg Reinisch
author_sort Gobert von Skrbensky
collection DOAJ
description Wear is a common cause for aseptic loosening in artificial joints. The purpose of this study was to develop an automated diagnostical method for identification of the number and size distribution of wear debris. For this purpose, metal debris samples were extracted from a hip simulator and then analyzed by the electrospray method combined with a differential mobility analyzer, allowing particle detection ranging from several nanometers up to 1 µm. Wear particles were identified with a characteristic peak at 15 nm. The electrospray setup was successfully used and validated for the first time to characterize wear debris from simulated total joint replacement. The advantages of this diagnostic method are its time- and financial efficiency and its suitability for testing of different materials.
first_indexed 2024-04-11T21:54:32Z
format Article
id doaj.art-e9b9afdf09644657b8eb3cae1db13c56
institution Directory Open Access Journal
issn 1424-8220
language English
last_indexed 2024-04-11T21:54:32Z
publishDate 2019-08-01
publisher MDPI AG
record_format Article
series Sensors
spelling doaj.art-e9b9afdf09644657b8eb3cae1db13c562022-12-22T04:01:09ZengMDPI AGSensors1424-82202019-08-011917375110.3390/s19173751s19173751Evaluation of Aerosol Electrospray Analysis of Metal-on-Metal Wear Particles from Simulated Total Joint ReplacementGobert von Skrbensky0Karoline Mühlbacher1Emir Benca2Alexander Kolb3Reinhard Windhager4Georg Reischl5Georg Reinisch6Department of Orthopedics and Trauma Surgery, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, AustriaFaculty of Physics, University of Vienna, Strudelhofgasse 4, 1090 Vienna, AustriaDepartment of Orthopedics and Trauma Surgery, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, AustriaDepartment of Orthopedics and Trauma Surgery, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, AustriaDepartment of Orthopedics and Trauma Surgery, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, AustriaIngenieurbüro für technische Physik, Speichmühlengasse 1, 2380 Perchtoldsdorf, AustriaBiomechanische Forschungs-Gesellschaft m.b.H., 1040 Vienna, AustriaWear is a common cause for aseptic loosening in artificial joints. The purpose of this study was to develop an automated diagnostical method for identification of the number and size distribution of wear debris. For this purpose, metal debris samples were extracted from a hip simulator and then analyzed by the electrospray method combined with a differential mobility analyzer, allowing particle detection ranging from several nanometers up to 1 µm. Wear particles were identified with a characteristic peak at 15 nm. The electrospray setup was successfully used and validated for the first time to characterize wear debris from simulated total joint replacement. The advantages of this diagnostic method are its time- and financial efficiency and its suitability for testing of different materials.https://www.mdpi.com/1424-8220/19/17/3751debrisparticleswearimplantsprosthesis
spellingShingle Gobert von Skrbensky
Karoline Mühlbacher
Emir Benca
Alexander Kolb
Reinhard Windhager
Georg Reischl
Georg Reinisch
Evaluation of Aerosol Electrospray Analysis of Metal-on-Metal Wear Particles from Simulated Total Joint Replacement
Sensors
debris
particles
wear
implants
prosthesis
title Evaluation of Aerosol Electrospray Analysis of Metal-on-Metal Wear Particles from Simulated Total Joint Replacement
title_full Evaluation of Aerosol Electrospray Analysis of Metal-on-Metal Wear Particles from Simulated Total Joint Replacement
title_fullStr Evaluation of Aerosol Electrospray Analysis of Metal-on-Metal Wear Particles from Simulated Total Joint Replacement
title_full_unstemmed Evaluation of Aerosol Electrospray Analysis of Metal-on-Metal Wear Particles from Simulated Total Joint Replacement
title_short Evaluation of Aerosol Electrospray Analysis of Metal-on-Metal Wear Particles from Simulated Total Joint Replacement
title_sort evaluation of aerosol electrospray analysis of metal on metal wear particles from simulated total joint replacement
topic debris
particles
wear
implants
prosthesis
url https://www.mdpi.com/1424-8220/19/17/3751
work_keys_str_mv AT gobertvonskrbensky evaluationofaerosolelectrosprayanalysisofmetalonmetalwearparticlesfromsimulatedtotaljointreplacement
AT karolinemuhlbacher evaluationofaerosolelectrosprayanalysisofmetalonmetalwearparticlesfromsimulatedtotaljointreplacement
AT emirbenca evaluationofaerosolelectrosprayanalysisofmetalonmetalwearparticlesfromsimulatedtotaljointreplacement
AT alexanderkolb evaluationofaerosolelectrosprayanalysisofmetalonmetalwearparticlesfromsimulatedtotaljointreplacement
AT reinhardwindhager evaluationofaerosolelectrosprayanalysisofmetalonmetalwearparticlesfromsimulatedtotaljointreplacement
AT georgreischl evaluationofaerosolelectrosprayanalysisofmetalonmetalwearparticlesfromsimulatedtotaljointreplacement
AT georgreinisch evaluationofaerosolelectrosprayanalysisofmetalonmetalwearparticlesfromsimulatedtotaljointreplacement