Exploring Chinese herbal medicine for the treatment of inflammatory bowel disease: A comprehensive overview

Introduction: Inflammatory Bowel Disease (IBD) is a recurrent and chronic inflammatory disorder that impacts the gastrointestinal tract. It is distinguished by a multiple etiology, including various complicated factors. The global prevalence of IBD has increased in recent years, leading to a need fo...

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Main Authors: Jeetendra Kumar Gupta, Aniruddh Pratap Singh, Yati Sharma
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Pharmacological Research - Modern Chinese Medicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667142524000253
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author Jeetendra Kumar Gupta
Aniruddh Pratap Singh
Yati Sharma
author_facet Jeetendra Kumar Gupta
Aniruddh Pratap Singh
Yati Sharma
author_sort Jeetendra Kumar Gupta
collection DOAJ
description Introduction: Inflammatory Bowel Disease (IBD) is a recurrent and chronic inflammatory disorder that impacts the gastrointestinal tract. It is distinguished by a multiple etiology, including various complicated factors. The global prevalence of IBD has increased in recent years, leading to a need for novel strategies in its management. This has sparked interest in exploring alternative medicines, such as herbal medicine, for the treatment of IBD. In this context, Chinese Herbal Medicine (CHM), which has a strong foundation in traditional practices, has garnered attention as a potentially successful exploration route owing to its diverse medicinal characteristics. Methodology: Different keywords, including IBD, CHM and Gut microbiota, were employed in searches across online databases like Scopus, Web of Science, Google Scholar, and PubMed. Duplicate references, inappropriate articles, and incomplete data were debarred which lies outside the scope of this artcle. Results: Although conventional treatments have demonstrated efficacy in certain patients, they frequently entail undesirable side effects and inherent constraints. This study provides a comprehensive analysis of the existing research literature about the effectiveness of several Chinese herbal formulations in reducing the symptoms associated with IBD and influencing the composition of the gut microbiota. Significant importance is attributed to comprehending the deep interrelationship between host-microbiota interactions and the intricate microbial populations that inhabit the gastrointestinal system. Discussion: The discussion delves into a comprehensive exploration of Chinese Herbal Medicine as a potential treatment option for Inflammatory Bowel Disease. This comprehensive review examines the diverse facets of complementary and alternative medicine in the management of IBD, encompassing its historical background, fundamental principles, the scientific rationale behind its effectiveness, and its practical implementation in clinical settings.
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spelling doaj.art-e9bf00d7f300447eb24cb118e9af91872024-03-21T05:38:05ZengElsevierPharmacological Research - Modern Chinese Medicine2667-14252024-03-0110100380Exploring Chinese herbal medicine for the treatment of inflammatory bowel disease: A comprehensive overviewJeetendra Kumar Gupta0Aniruddh Pratap Singh1Yati Sharma2Corresponding author.; Institute of Pharmaceutical Research, GLA University Mathura, Uttar Pradesh, IndiaInstitute of Pharmaceutical Research, GLA University Mathura, Uttar Pradesh, IndiaInstitute of Pharmaceutical Research, GLA University Mathura, Uttar Pradesh, IndiaIntroduction: Inflammatory Bowel Disease (IBD) is a recurrent and chronic inflammatory disorder that impacts the gastrointestinal tract. It is distinguished by a multiple etiology, including various complicated factors. The global prevalence of IBD has increased in recent years, leading to a need for novel strategies in its management. This has sparked interest in exploring alternative medicines, such as herbal medicine, for the treatment of IBD. In this context, Chinese Herbal Medicine (CHM), which has a strong foundation in traditional practices, has garnered attention as a potentially successful exploration route owing to its diverse medicinal characteristics. Methodology: Different keywords, including IBD, CHM and Gut microbiota, were employed in searches across online databases like Scopus, Web of Science, Google Scholar, and PubMed. Duplicate references, inappropriate articles, and incomplete data were debarred which lies outside the scope of this artcle. Results: Although conventional treatments have demonstrated efficacy in certain patients, they frequently entail undesirable side effects and inherent constraints. This study provides a comprehensive analysis of the existing research literature about the effectiveness of several Chinese herbal formulations in reducing the symptoms associated with IBD and influencing the composition of the gut microbiota. Significant importance is attributed to comprehending the deep interrelationship between host-microbiota interactions and the intricate microbial populations that inhabit the gastrointestinal system. Discussion: The discussion delves into a comprehensive exploration of Chinese Herbal Medicine as a potential treatment option for Inflammatory Bowel Disease. This comprehensive review examines the diverse facets of complementary and alternative medicine in the management of IBD, encompassing its historical background, fundamental principles, the scientific rationale behind its effectiveness, and its practical implementation in clinical settings.http://www.sciencedirect.com/science/article/pii/S2667142524000253Inflammatory bowel diseaseChinese herbal medicineGut microbiotaQingchang huashiFufangkushen colon-coated capsule
spellingShingle Jeetendra Kumar Gupta
Aniruddh Pratap Singh
Yati Sharma
Exploring Chinese herbal medicine for the treatment of inflammatory bowel disease: A comprehensive overview
Pharmacological Research - Modern Chinese Medicine
Inflammatory bowel disease
Chinese herbal medicine
Gut microbiota
Qingchang huashi
Fufangkushen colon-coated capsule
title Exploring Chinese herbal medicine for the treatment of inflammatory bowel disease: A comprehensive overview
title_full Exploring Chinese herbal medicine for the treatment of inflammatory bowel disease: A comprehensive overview
title_fullStr Exploring Chinese herbal medicine for the treatment of inflammatory bowel disease: A comprehensive overview
title_full_unstemmed Exploring Chinese herbal medicine for the treatment of inflammatory bowel disease: A comprehensive overview
title_short Exploring Chinese herbal medicine for the treatment of inflammatory bowel disease: A comprehensive overview
title_sort exploring chinese herbal medicine for the treatment of inflammatory bowel disease a comprehensive overview
topic Inflammatory bowel disease
Chinese herbal medicine
Gut microbiota
Qingchang huashi
Fufangkushen colon-coated capsule
url http://www.sciencedirect.com/science/article/pii/S2667142524000253
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