Association of Radiation Doses and Cancer Risks from CT Pulmonary Angiography Examinations in Relation to Body Diameter
In this study, we aimed to estimate the probability of cancer risk induced by CT pulmonary angiography (CTPA) examinations concerning effective body diameter. One hundred patients who underwent CTPA examinations were recruited as subjects from a single institution in Kuala Lumpur. Subjects were cate...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-09-01
|
| Series: | Diagnostics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2075-4418/10/9/681 |
| _version_ | 1797554173011558400 |
|---|---|
| author | Hanif Haspi Harun Muhammad Khalis Abdul Karim Zulkifly Abbas Mohd Amir Abdul Rahman Akmal Sabarudin Kwan Hoong Ng |
| author_facet | Hanif Haspi Harun Muhammad Khalis Abdul Karim Zulkifly Abbas Mohd Amir Abdul Rahman Akmal Sabarudin Kwan Hoong Ng |
| author_sort | Hanif Haspi Harun |
| collection | DOAJ |
| description | In this study, we aimed to estimate the probability of cancer risk induced by CT pulmonary angiography (CTPA) examinations concerning effective body diameter. One hundred patients who underwent CTPA examinations were recruited as subjects from a single institution in Kuala Lumpur. Subjects were categorized based on their effective diameter size, where 19–25, 25–28, and >28 cm categorized as Groups 1, 2, and 3, respectively. The mean value of the body diameter of the subjects was 26.82 ± 3.12 cm, with no significant differences found between male and female subjects. The risk of cancer in breast, lung, and liver organs was 0.009%, 0.007%, and 0.005% respectively. The volume-weighted CT dose index (CTDI<sub>vol</sub>) was underestimated, whereas the size-specific dose estimates (SSDEs) provided a more accurate description of the radiation dose and the risk of cancer. CTPA examinations are considered safe but it is essential to implement a protocol optimized following the As Low as Reasonably Achievable (ALARA) principle. |
| first_indexed | 2024-03-10T16:28:04Z |
| format | Article |
| id | doaj.art-e9c01b71a63747adbbbcdc14a029d026 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-10T16:28:04Z |
| publishDate | 2020-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-e9c01b71a63747adbbbcdc14a029d0262023-11-20T13:08:41ZengMDPI AGDiagnostics2075-44182020-09-0110968110.3390/diagnostics10090681Association of Radiation Doses and Cancer Risks from CT Pulmonary Angiography Examinations in Relation to Body DiameterHanif Haspi Harun0Muhammad Khalis Abdul Karim1Zulkifly Abbas2Mohd Amir Abdul Rahman3Akmal Sabarudin4Kwan Hoong Ng5Department of Physics, Faculty of Science, Universiti Putra Malaysia, Serdang 43400, Selangor, MalaysiaDepartment of Physics, Faculty of Science, Universiti Putra Malaysia, Serdang 43400, Selangor, MalaysiaDepartment of Physics, Faculty of Science, Universiti Putra Malaysia, Serdang 43400, Selangor, MalaysiaDepartment of Physics, Faculty of Science, Universiti Putra Malaysia, Serdang 43400, Selangor, MalaysiaDepartment of Diagnostic & Applied Health Sciences, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, MalaysiaDepartment of Biomedical Imaging, Faculty of Medicine, Universiti Malaya, Kuala Lumpur 50603, MalaysiaIn this study, we aimed to estimate the probability of cancer risk induced by CT pulmonary angiography (CTPA) examinations concerning effective body diameter. One hundred patients who underwent CTPA examinations were recruited as subjects from a single institution in Kuala Lumpur. Subjects were categorized based on their effective diameter size, where 19–25, 25–28, and >28 cm categorized as Groups 1, 2, and 3, respectively. The mean value of the body diameter of the subjects was 26.82 ± 3.12 cm, with no significant differences found between male and female subjects. The risk of cancer in breast, lung, and liver organs was 0.009%, 0.007%, and 0.005% respectively. The volume-weighted CT dose index (CTDI<sub>vol</sub>) was underestimated, whereas the size-specific dose estimates (SSDEs) provided a more accurate description of the radiation dose and the risk of cancer. CTPA examinations are considered safe but it is essential to implement a protocol optimized following the As Low as Reasonably Achievable (ALARA) principle.https://www.mdpi.com/2075-4418/10/9/681radiation dosecancer riskCTPA examinationsbody diameterSSDE |
| spellingShingle | Hanif Haspi Harun Muhammad Khalis Abdul Karim Zulkifly Abbas Mohd Amir Abdul Rahman Akmal Sabarudin Kwan Hoong Ng Association of Radiation Doses and Cancer Risks from CT Pulmonary Angiography Examinations in Relation to Body Diameter Diagnostics radiation dose cancer risk CTPA examinations body diameter SSDE |
| title | Association of Radiation Doses and Cancer Risks from CT Pulmonary Angiography Examinations in Relation to Body Diameter |
| title_full | Association of Radiation Doses and Cancer Risks from CT Pulmonary Angiography Examinations in Relation to Body Diameter |
| title_fullStr | Association of Radiation Doses and Cancer Risks from CT Pulmonary Angiography Examinations in Relation to Body Diameter |
| title_full_unstemmed | Association of Radiation Doses and Cancer Risks from CT Pulmonary Angiography Examinations in Relation to Body Diameter |
| title_short | Association of Radiation Doses and Cancer Risks from CT Pulmonary Angiography Examinations in Relation to Body Diameter |
| title_sort | association of radiation doses and cancer risks from ct pulmonary angiography examinations in relation to body diameter |
| topic | radiation dose cancer risk CTPA examinations body diameter SSDE |
| url | https://www.mdpi.com/2075-4418/10/9/681 |
| work_keys_str_mv | AT hanifhaspiharun associationofradiationdosesandcancerrisksfromctpulmonaryangiographyexaminationsinrelationtobodydiameter AT muhammadkhalisabdulkarim associationofradiationdosesandcancerrisksfromctpulmonaryangiographyexaminationsinrelationtobodydiameter AT zulkiflyabbas associationofradiationdosesandcancerrisksfromctpulmonaryangiographyexaminationsinrelationtobodydiameter AT mohdamirabdulrahman associationofradiationdosesandcancerrisksfromctpulmonaryangiographyexaminationsinrelationtobodydiameter AT akmalsabarudin associationofradiationdosesandcancerrisksfromctpulmonaryangiographyexaminationsinrelationtobodydiameter AT kwanhoongng associationofradiationdosesandcancerrisksfromctpulmonaryangiographyexaminationsinrelationtobodydiameter |