Alteration in pattern reversal visual evoked potential in pediatric population with amblyopia and spherical refractive errors
Purpose: To study the effect of refractive errors on pattern visual evoked potential (VEP) recordings in the pediatric population. Methods: This cross-sectional observational study assessed 240 eyes of 120 participants attending the outpatient department of a tertiary care center in North India. Par...
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| Format: | Article |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Indian Journal of Ophthalmology |
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| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2022;volume=70;issue=5;spage=1727;epage=1731;aulast=Agrawal |
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| author | Ajai Agrawal Athul Suresh Puthalath Sanjeev K Mittal Sunita Mittal Yogesh Singh Anupam Singh |
| author_facet | Ajai Agrawal Athul Suresh Puthalath Sanjeev K Mittal Sunita Mittal Yogesh Singh Anupam Singh |
| author_sort | Ajai Agrawal |
| collection | DOAJ |
| description | Purpose: To study the effect of refractive errors on pattern visual evoked potential (VEP) recordings in the pediatric population. Methods: This cross-sectional observational study assessed 240 eyes of 120 participants attending the outpatient department of a tertiary care center in North India. Participants were between 8 and 18 years of age; 30 participants each were recruited into four groups, namely emmetropia, myopia, hypermetropia, and amblyopia. They were then subjected to pattern reversal VEP, with P-100 amplitude and latency recorded for each participant. Results: The emmetropic group in this study provided normal values of P-100 parameters, namely P-100 latency and P-100 amplitude with readings of 115.78 ± 10.19 ms and 11.11 ± 4.08 μV, respectively. P-100 amplitude was significant compared to P-100 latency in detecting the presence or absence of a specific type of refractive error. It was found that there was a significant association between severity of myopia and P-100 latency (both unaided and aided) with P < 0.05. The severity of hypermetropia showed a significant association with P-100 amplitude (unaided) (P < 0.05). Receiver operating characteristics analysis revealed P-100 amplitude to be a good predictor of refractive error and the cut-offs were calculated. Conclusion: The P-100 parameters of the pediatric Indian population were comparatively higher than conventional values. P-100 latency seemed to better correlate with myopia, while hypermetropia correlated with P-100 amplitude. P-100 amplitude appears to be the most significant predictor of the presence of refractive error in an individual. |
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| format | Article |
| id | doaj.art-e9c099939b9743e193bc1d59fe58d506 |
| institution | Directory Open Access Journal |
| issn | 0301-4738 1998-3689 |
| language | English |
| last_indexed | 2024-04-12T14:31:04Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-e9c099939b9743e193bc1d59fe58d5062022-12-22T03:29:17ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892022-01-017051727173110.4103/ijo.IJO_2692_21Alteration in pattern reversal visual evoked potential in pediatric population with amblyopia and spherical refractive errorsAjai AgrawalAthul Suresh PuthalathSanjeev K MittalSunita MittalYogesh SinghAnupam SinghPurpose: To study the effect of refractive errors on pattern visual evoked potential (VEP) recordings in the pediatric population. Methods: This cross-sectional observational study assessed 240 eyes of 120 participants attending the outpatient department of a tertiary care center in North India. Participants were between 8 and 18 years of age; 30 participants each were recruited into four groups, namely emmetropia, myopia, hypermetropia, and amblyopia. They were then subjected to pattern reversal VEP, with P-100 amplitude and latency recorded for each participant. Results: The emmetropic group in this study provided normal values of P-100 parameters, namely P-100 latency and P-100 amplitude with readings of 115.78 ± 10.19 ms and 11.11 ± 4.08 μV, respectively. P-100 amplitude was significant compared to P-100 latency in detecting the presence or absence of a specific type of refractive error. It was found that there was a significant association between severity of myopia and P-100 latency (both unaided and aided) with P < 0.05. The severity of hypermetropia showed a significant association with P-100 amplitude (unaided) (P < 0.05). Receiver operating characteristics analysis revealed P-100 amplitude to be a good predictor of refractive error and the cut-offs were calculated. Conclusion: The P-100 parameters of the pediatric Indian population were comparatively higher than conventional values. P-100 latency seemed to better correlate with myopia, while hypermetropia correlated with P-100 amplitude. P-100 amplitude appears to be the most significant predictor of the presence of refractive error in an individual.http://www.ijo.in/article.asp?issn=0301-4738;year=2022;volume=70;issue=5;spage=1727;epage=1731;aulast=Agrawalamblyopiahypermetropiamyopiap-100pediatricrefractive errorvisual evoked potential |
| spellingShingle | Ajai Agrawal Athul Suresh Puthalath Sanjeev K Mittal Sunita Mittal Yogesh Singh Anupam Singh Alteration in pattern reversal visual evoked potential in pediatric population with amblyopia and spherical refractive errors Indian Journal of Ophthalmology amblyopia hypermetropia myopia p-100 pediatric refractive error visual evoked potential |
| title | Alteration in pattern reversal visual evoked potential in pediatric population with amblyopia and spherical refractive errors |
| title_full | Alteration in pattern reversal visual evoked potential in pediatric population with amblyopia and spherical refractive errors |
| title_fullStr | Alteration in pattern reversal visual evoked potential in pediatric population with amblyopia and spherical refractive errors |
| title_full_unstemmed | Alteration in pattern reversal visual evoked potential in pediatric population with amblyopia and spherical refractive errors |
| title_short | Alteration in pattern reversal visual evoked potential in pediatric population with amblyopia and spherical refractive errors |
| title_sort | alteration in pattern reversal visual evoked potential in pediatric population with amblyopia and spherical refractive errors |
| topic | amblyopia hypermetropia myopia p-100 pediatric refractive error visual evoked potential |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=2022;volume=70;issue=5;spage=1727;epage=1731;aulast=Agrawal |
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