Neuroprotective effects of α-lipoic acid on the development of oxidative stress and astrogliosis in the brain of STZ-diabetic rats

The aim of this study was to examine whether the antioxidant alpha-lipoic acid protects neurons from diabetic-reperfusion injury. The streptozotocin (STZ) rat model was used to study the glial reactivity and prevention of gliosis by alpha-lipoic acid (alpha-LA) administration. The expression of glia...

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Bibliographic Details
Main Authors: S. Kyrychenko, I. Prishchepa, V. Lagoda, M. Velika, V. Nedzvetsky
Format: Article
Language:English
Published: Oles Honchar Dnipropetrovsk National University 2014-07-01
Series:Vìsnik Dnìpropetrovsʹkogo Unìversitetu: Serìâ Bìologìâ, Medicina
Subjects:
Online Access:http://medicine.dp.ua/index.php/med/article/view/233