Item Selection for a New Health-Related Quality of Life Measure for Parkinson’s Disease: The Preference-Based Parkinson’s Disease Index (PB-PDI)
Background. Parkinson’s disease (PD) is a neurodegenerative condition, predominantly affecting older adults. Preference-based measures (PBMs) can be used to make decisions about the cost-utility of different treatments. There are currently no PBMs for health-related quality of life (HRQoL) for PD. A...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-01-01
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| Series: | Neurology Research International |
| Online Access: | http://dx.doi.org/10.1155/2023/6559857 |
| _version_ | 1826822955718410240 |
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| author | Selina Malouka Lizabeth Teshler Nancy Mayo Marla Beauchamp Julie Richardson Ayse Kuspinar |
| author_facet | Selina Malouka Lizabeth Teshler Nancy Mayo Marla Beauchamp Julie Richardson Ayse Kuspinar |
| author_sort | Selina Malouka |
| collection | DOAJ |
| description | Background. Parkinson’s disease (PD) is a neurodegenerative condition, predominantly affecting older adults. Preference-based measures (PBMs) can be used to make decisions about the cost-utility of different treatments. There are currently no PBMs for health-related quality of life (HRQoL) for PD. A previous study identified important health domains for individuals with PD and developed an item pool from existing measures per domain. The current study aims to contribute to the development of a new disease-specific PBM of HRQoL for PD by reducing the current pool of items according to the preferences of individuals with PD. Methods. Fifty-three participants completed a visual analogue scale (VAS) of self-perceived health, the prototype PBM measure, and an item importance rating. To reduce the item pool, the following were calculated: (1) inter-item correlations; (2) impact of each item based on item performance and importance rating; (3) directionality of response options by comparing the VAS scores against each item. Results. Participants (male = 54.7%, age = 60.0 ± 10.2) had a median Hoehn and Yahr score of 2.5 (interquartile range = 1). Items supported for inclusion by this analysis were sleep, fatigue, tremor, mood, walking, memory, and dexterity. Items demonstrating a logical decrease in VAS score with each increasing severity level were sleep, memory, tremor, fatigue, and mood. Conclusion. This PBM will be critical for informing decisions about the cost-utility of PD treatments, guiding the resource allocation within our healthcare system. Future research will include cognitive debriefing with individuals with PD to refine item response options. |
| first_indexed | 2024-04-10T19:39:18Z |
| format | Article |
| id | doaj.art-e9c4cbf62ecb4bbc89ea8516b8c514fb |
| institution | Directory Open Access Journal |
| issn | 2090-1860 |
| language | English |
| last_indexed | 2025-02-16T07:14:03Z |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Neurology Research International |
| spelling | doaj.art-e9c4cbf62ecb4bbc89ea8516b8c514fb2025-02-03T06:08:39ZengWileyNeurology Research International2090-18602023-01-01202310.1155/2023/6559857Item Selection for a New Health-Related Quality of Life Measure for Parkinson’s Disease: The Preference-Based Parkinson’s Disease Index (PB-PDI)Selina Malouka0Lizabeth Teshler1Nancy Mayo2Marla Beauchamp3Julie Richardson4Ayse Kuspinar5School of Rehabilitation ScienceArts and Science ProgramCenter for Outcomes Research and EvaluationSchool of Rehabilitation ScienceSchool of Rehabilitation ScienceSchool of Rehabilitation ScienceBackground. Parkinson’s disease (PD) is a neurodegenerative condition, predominantly affecting older adults. Preference-based measures (PBMs) can be used to make decisions about the cost-utility of different treatments. There are currently no PBMs for health-related quality of life (HRQoL) for PD. A previous study identified important health domains for individuals with PD and developed an item pool from existing measures per domain. The current study aims to contribute to the development of a new disease-specific PBM of HRQoL for PD by reducing the current pool of items according to the preferences of individuals with PD. Methods. Fifty-three participants completed a visual analogue scale (VAS) of self-perceived health, the prototype PBM measure, and an item importance rating. To reduce the item pool, the following were calculated: (1) inter-item correlations; (2) impact of each item based on item performance and importance rating; (3) directionality of response options by comparing the VAS scores against each item. Results. Participants (male = 54.7%, age = 60.0 ± 10.2) had a median Hoehn and Yahr score of 2.5 (interquartile range = 1). Items supported for inclusion by this analysis were sleep, fatigue, tremor, mood, walking, memory, and dexterity. Items demonstrating a logical decrease in VAS score with each increasing severity level were sleep, memory, tremor, fatigue, and mood. Conclusion. This PBM will be critical for informing decisions about the cost-utility of PD treatments, guiding the resource allocation within our healthcare system. Future research will include cognitive debriefing with individuals with PD to refine item response options.http://dx.doi.org/10.1155/2023/6559857 |
| spellingShingle | Selina Malouka Lizabeth Teshler Nancy Mayo Marla Beauchamp Julie Richardson Ayse Kuspinar Item Selection for a New Health-Related Quality of Life Measure for Parkinson’s Disease: The Preference-Based Parkinson’s Disease Index (PB-PDI) Neurology Research International |
| title | Item Selection for a New Health-Related Quality of Life Measure for Parkinson’s Disease: The Preference-Based Parkinson’s Disease Index (PB-PDI) |
| title_full | Item Selection for a New Health-Related Quality of Life Measure for Parkinson’s Disease: The Preference-Based Parkinson’s Disease Index (PB-PDI) |
| title_fullStr | Item Selection for a New Health-Related Quality of Life Measure for Parkinson’s Disease: The Preference-Based Parkinson’s Disease Index (PB-PDI) |
| title_full_unstemmed | Item Selection for a New Health-Related Quality of Life Measure for Parkinson’s Disease: The Preference-Based Parkinson’s Disease Index (PB-PDI) |
| title_short | Item Selection for a New Health-Related Quality of Life Measure for Parkinson’s Disease: The Preference-Based Parkinson’s Disease Index (PB-PDI) |
| title_sort | item selection for a new health related quality of life measure for parkinson s disease the preference based parkinson s disease index pb pdi |
| url | http://dx.doi.org/10.1155/2023/6559857 |
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