Oligodendrocytes express synaptic proteins that modulate myelin sheath formation
Oligodendrocyte processes can detect and respond to axonal vesicular release. The authors here show in zebrafish that transsynaptic adhesion molecules, molecules that promote synapse formation and maturation in neurons, are expressed by oligodendrocytes and required for myelin sheath growth.
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2019-09-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-019-12059-y |
| _version_ | 1819035847305986048 |
|---|---|
| author | Alexandria N. Hughes Bruce Appel |
| author_facet | Alexandria N. Hughes Bruce Appel |
| author_sort | Alexandria N. Hughes |
| collection | DOAJ |
| description | Oligodendrocyte processes can detect and respond to axonal vesicular release. The authors here show in zebrafish that transsynaptic adhesion molecules, molecules that promote synapse formation and maturation in neurons, are expressed by oligodendrocytes and required for myelin sheath growth. |
| first_indexed | 2024-12-21T07:56:08Z |
| format | Article |
| id | doaj.art-e9c64b7049824e3d9095fa2e8fa64bfa |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-21T07:56:08Z |
| publishDate | 2019-09-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-e9c64b7049824e3d9095fa2e8fa64bfa2022-12-21T19:10:59ZengNature PortfolioNature Communications2041-17232019-09-0110111510.1038/s41467-019-12059-yOligodendrocytes express synaptic proteins that modulate myelin sheath formationAlexandria N. Hughes0Bruce Appel1University of Colorado School of Medicine, Anschutz Medical CampusUniversity of Colorado School of Medicine, Anschutz Medical CampusOligodendrocyte processes can detect and respond to axonal vesicular release. The authors here show in zebrafish that transsynaptic adhesion molecules, molecules that promote synapse formation and maturation in neurons, are expressed by oligodendrocytes and required for myelin sheath growth.https://doi.org/10.1038/s41467-019-12059-y |
| spellingShingle | Alexandria N. Hughes Bruce Appel Oligodendrocytes express synaptic proteins that modulate myelin sheath formation Nature Communications |
| title | Oligodendrocytes express synaptic proteins that modulate myelin sheath formation |
| title_full | Oligodendrocytes express synaptic proteins that modulate myelin sheath formation |
| title_fullStr | Oligodendrocytes express synaptic proteins that modulate myelin sheath formation |
| title_full_unstemmed | Oligodendrocytes express synaptic proteins that modulate myelin sheath formation |
| title_short | Oligodendrocytes express synaptic proteins that modulate myelin sheath formation |
| title_sort | oligodendrocytes express synaptic proteins that modulate myelin sheath formation |
| url | https://doi.org/10.1038/s41467-019-12059-y |
| work_keys_str_mv | AT alexandrianhughes oligodendrocytesexpresssynapticproteinsthatmodulatemyelinsheathformation AT bruceappel oligodendrocytesexpresssynapticproteinsthatmodulatemyelinsheathformation |