Number of vaginal lactobacilli in postmenopausal women with vaginal atrophy before and after treatment with erbium–YAG laser: a randomized sham-controlled trial
Abstract Primary objective To evaluate the effect of erbium–YAG laser on the number of vaginal lactobacilli in postmenopausal women. Secondary objectives To evaluate the effect of erbium–YAG laser on vaginal atrophy symptoms and vaginal pH in postmenopausal women. Materials and methods A total of 44...
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| Format: | Article |
| Language: | English |
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BMC
2023-09-01
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| Series: | BMC Women's Health |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12905-023-02590-y |
| _version_ | 1797451653381619712 |
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| author | Nuttanun Panyawongudom Krasean Panyakhamlerd Ammarin Suwan |
| author_facet | Nuttanun Panyawongudom Krasean Panyakhamlerd Ammarin Suwan |
| author_sort | Nuttanun Panyawongudom |
| collection | DOAJ |
| description | Abstract Primary objective To evaluate the effect of erbium–YAG laser on the number of vaginal lactobacilli in postmenopausal women. Secondary objectives To evaluate the effect of erbium–YAG laser on vaginal atrophy symptoms and vaginal pH in postmenopausal women. Materials and methods A total of 44 postmenopausal women who met the inclusion criteria were randomized in the laser group (n = 22) and sham group (n = 22). Vaginal lactobacilli grading, vaginal pH, vaginal atrophy score, and vaginal atrophy symptoms were assessed before and after treatment with erbium–YAG laser for two consecutive times, with a four-week interval; the results were compared with the effects of the sham procedure. Any adverse events after the treatment were recorded. Results A total of 44 women were included, and five were lost to follow-up. Compared with sham procedure, vaginal lactobacilli grading improved in the laser group (5/20 in the laser group and 1/19 in the sham group). However, the improvement did not reach statistical significance (adjusted odds ratio = 5.32, 95% CI = 0.5–56.21). Vaginal atrophy symptoms measured by the visual analog scale (VAS) and vaginal pH were improved in both groups without a statistically significant difference between the two groups. Vaginal “dryness” VAS and vaginal atrophy score after treatment were significantly lowered in the laser group compared with the sham group. Conclusions This study showed an improvement in vaginal lactobacilli grading after vaginal laser treatment. However, the difference in vaginal lactobacilli grading after treatment in both groups was not statistically significant. |
| first_indexed | 2024-03-09T14:57:35Z |
| format | Article |
| id | doaj.art-e9c745b65bca4409b0136a5362e636ea |
| institution | Directory Open Access Journal |
| issn | 1472-6874 |
| language | English |
| last_indexed | 2024-03-09T14:57:35Z |
| publishDate | 2023-09-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Women's Health |
| spelling | doaj.art-e9c745b65bca4409b0136a5362e636ea2023-11-26T14:06:49ZengBMCBMC Women's Health1472-68742023-09-012311710.1186/s12905-023-02590-yNumber of vaginal lactobacilli in postmenopausal women with vaginal atrophy before and after treatment with erbium–YAG laser: a randomized sham-controlled trialNuttanun Panyawongudom0Krasean Panyakhamlerd1Ammarin Suwan2Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn UniversityDepartment of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn UniversityDepartment of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn UniversityAbstract Primary objective To evaluate the effect of erbium–YAG laser on the number of vaginal lactobacilli in postmenopausal women. Secondary objectives To evaluate the effect of erbium–YAG laser on vaginal atrophy symptoms and vaginal pH in postmenopausal women. Materials and methods A total of 44 postmenopausal women who met the inclusion criteria were randomized in the laser group (n = 22) and sham group (n = 22). Vaginal lactobacilli grading, vaginal pH, vaginal atrophy score, and vaginal atrophy symptoms were assessed before and after treatment with erbium–YAG laser for two consecutive times, with a four-week interval; the results were compared with the effects of the sham procedure. Any adverse events after the treatment were recorded. Results A total of 44 women were included, and five were lost to follow-up. Compared with sham procedure, vaginal lactobacilli grading improved in the laser group (5/20 in the laser group and 1/19 in the sham group). However, the improvement did not reach statistical significance (adjusted odds ratio = 5.32, 95% CI = 0.5–56.21). Vaginal atrophy symptoms measured by the visual analog scale (VAS) and vaginal pH were improved in both groups without a statistically significant difference between the two groups. Vaginal “dryness” VAS and vaginal atrophy score after treatment were significantly lowered in the laser group compared with the sham group. Conclusions This study showed an improvement in vaginal lactobacilli grading after vaginal laser treatment. However, the difference in vaginal lactobacilli grading after treatment in both groups was not statistically significant.https://doi.org/10.1186/s12905-023-02590-yErbium–YAG laserVaginal lactobacilliRandomized sham-controlled trialMenopauseVaginal atrophyVaginal pH |
| spellingShingle | Nuttanun Panyawongudom Krasean Panyakhamlerd Ammarin Suwan Number of vaginal lactobacilli in postmenopausal women with vaginal atrophy before and after treatment with erbium–YAG laser: a randomized sham-controlled trial BMC Women's Health Erbium–YAG laser Vaginal lactobacilli Randomized sham-controlled trial Menopause Vaginal atrophy Vaginal pH |
| title | Number of vaginal lactobacilli in postmenopausal women with vaginal atrophy before and after treatment with erbium–YAG laser: a randomized sham-controlled trial |
| title_full | Number of vaginal lactobacilli in postmenopausal women with vaginal atrophy before and after treatment with erbium–YAG laser: a randomized sham-controlled trial |
| title_fullStr | Number of vaginal lactobacilli in postmenopausal women with vaginal atrophy before and after treatment with erbium–YAG laser: a randomized sham-controlled trial |
| title_full_unstemmed | Number of vaginal lactobacilli in postmenopausal women with vaginal atrophy before and after treatment with erbium–YAG laser: a randomized sham-controlled trial |
| title_short | Number of vaginal lactobacilli in postmenopausal women with vaginal atrophy before and after treatment with erbium–YAG laser: a randomized sham-controlled trial |
| title_sort | number of vaginal lactobacilli in postmenopausal women with vaginal atrophy before and after treatment with erbium yag laser a randomized sham controlled trial |
| topic | Erbium–YAG laser Vaginal lactobacilli Randomized sham-controlled trial Menopause Vaginal atrophy Vaginal pH |
| url | https://doi.org/10.1186/s12905-023-02590-y |
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