Germline and somatic drivers in inherited hematologic malignancies

Inherited hematologic malignancies are linked to a heterogenous group of genes, knowledge of which is rapidly expanding using panel-based next-generation sequencing (NGS) or whole-exome/whole-genome sequencing. Importantly, the penetrance for these syndromes is incomplete, and disease development, p...

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Podrobná bibliografie
Hlavní autoři: Julian Zoller, Despina Trajanova, Simone Feurstein
Médium: Článek
Jazyk:English
Vydáno: Frontiers Media S.A. 2023-10-01
Edice:Frontiers in Oncology
Témata:
On-line přístup:https://www.frontiersin.org/articles/10.3389/fonc.2023.1205855/full