Optimal Design of Novel Microemulsions-Based Two-Layered Dissolving Microneedles for Delivering Fluconazole in Treatment of Fungal Eye Infection

Optimal Design of Novel Microemulsions-Based Two-Layered Dissolving Microneedles for Delivering Fluconazole in Treatment of Fungal Eye Infection

The optimal design of novel microneedles (MNs) for the ocular delivery system is necessary and useful for improving the effectiveness of medication. The objective of this study was to design and develop the optimal fluconazole (FLUZ)-microemulsions (MEs)-loaded two-layered dissolving MNs as a potent...

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Bibliographic Details
Main Authors: Phuvamin Suriyaamporn, Praneet Opanasopit, Worranan Rangsimawong, Tanasait Ngawhirunpat
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Pharmaceutics
Subjects:
two-layered dissolving microneedles
microemulsion
optimal mixture design
fungal keratitis
fluconazole
Online Access:https://www.mdpi.com/1999-4923/14/3/472

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