Metformin Attenuates TGF-β1-Induced Fibrosis in Salivary Gland: A Preliminary Study

Metformin Attenuates TGF-β1-Induced Fibrosis in Salivary Gland: A Preliminary Study

Fibrosis commonly arises from salivary gland injuries induced by factors such as inflammation, ductal obstruction, radiation, aging, and autoimmunity, leading to glandular atrophy and functional impairment. However, effective treatments for these injuries remain elusive. Transforming growth factor-b...

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Bibliographic Details
Main Authors:	Lianhao Wang, Nian-Nian Zhong, Xiaofeng Wang, Boyuan Peng, Zhuo Chen, Lili Wei, Bo Li, Yuhong Li, Yong Cheng
Format:	Article
Language:	English
Published:	MDPI AG 2023-11-01
Series:	International Journal of Molecular Sciences
Subjects:	submandibular gland fibrogenesis NADPH Oxidase 4 reactive oxygen species AMP-activated protein kinases fibroblast
Online Access:	https://www.mdpi.com/1422-0067/24/22/16260

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