Case Report: Desmoid tumor response to magnetic resonance-guided high intensity focused ultrasound over 4 years
Desmoid tumors are a rare form of cancer, which show locally aggressive invasion of surrounding tissues and may occur anywhere in the body. Treatment options comprise conservative watch and wait strategies as tumors may show spontaneous regression as well as surgical resection, radiation therapy, no...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-06-01
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| Series: | Frontiers in Oncology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2023.1124244/full |
| _version_ | 1827929573312954368 |
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| author | Sin Yuin Yeo Grischa Bratke Peter Knöll Sebastian Gottfried Walter David Maintz Holger Grüll Holger Grüll |
| author_facet | Sin Yuin Yeo Grischa Bratke Peter Knöll Sebastian Gottfried Walter David Maintz Holger Grüll Holger Grüll |
| author_sort | Sin Yuin Yeo |
| collection | DOAJ |
| description | Desmoid tumors are a rare form of cancer, which show locally aggressive invasion of surrounding tissues and may occur anywhere in the body. Treatment options comprise conservative watch and wait strategies as tumors may show spontaneous regression as well as surgical resection, radiation therapy, nonsteroidal anti-inflammatory drugs (NSAID), chemotherapy, or local thermoablative approaches for progressive disease. The latter comprises cryotherapy, radiofrequency, microwave ablation, or thermal ablation with high intensity focused ultrasound (HIFU) as the only entirely non-invasive option. This report presents a case where a desmoid tumor at the left dorsal humerus was 2 times surgically resected and, after recurrence, thermally ablated with HIFU under magnetic resonance image-guidance (MR-HIFU). In our report, we analyze tumor volume and/or pain score during standard of care (2 years) and after HIFU treatment over a 4-year follow-up period. Results showed MR-HIFU treatment led to complete tumor remission and pain response. |
| first_indexed | 2024-03-13T06:24:16Z |
| format | Article |
| id | doaj.art-e9d45b0fa2864ed0b8609beee0ba821f |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-03-13T06:24:16Z |
| publishDate | 2023-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-e9d45b0fa2864ed0b8609beee0ba821f2023-06-09T11:11:35ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2023-06-011310.3389/fonc.2023.11242441124244Case Report: Desmoid tumor response to magnetic resonance-guided high intensity focused ultrasound over 4 yearsSin Yuin Yeo0Grischa Bratke1Peter Knöll2Sebastian Gottfried Walter3David Maintz4Holger Grüll5Holger Grüll6Institute of Diagnostic and Interventional Radiology, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, GermanyInstitute of Diagnostic and Interventional Radiology, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, GermanyDepartment of Orthopedic Surgery and Traumatology, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, GermanyDepartment of Orthopedic Surgery and Traumatology, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, GermanyInstitute of Diagnostic and Interventional Radiology, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, GermanyInstitute of Diagnostic and Interventional Radiology, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, GermanyDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, University of Cologne, Cologne, GermanyDesmoid tumors are a rare form of cancer, which show locally aggressive invasion of surrounding tissues and may occur anywhere in the body. Treatment options comprise conservative watch and wait strategies as tumors may show spontaneous regression as well as surgical resection, radiation therapy, nonsteroidal anti-inflammatory drugs (NSAID), chemotherapy, or local thermoablative approaches for progressive disease. The latter comprises cryotherapy, radiofrequency, microwave ablation, or thermal ablation with high intensity focused ultrasound (HIFU) as the only entirely non-invasive option. This report presents a case where a desmoid tumor at the left dorsal humerus was 2 times surgically resected and, after recurrence, thermally ablated with HIFU under magnetic resonance image-guidance (MR-HIFU). In our report, we analyze tumor volume and/or pain score during standard of care (2 years) and after HIFU treatment over a 4-year follow-up period. Results showed MR-HIFU treatment led to complete tumor remission and pain response.https://www.frontiersin.org/articles/10.3389/fonc.2023.1124244/fullHIFUMR-HIFUfocused ultrasoundmagnetic resonance-guided high intensity focused ultrasounddesmoid tumortumor control |
| spellingShingle | Sin Yuin Yeo Grischa Bratke Peter Knöll Sebastian Gottfried Walter David Maintz Holger Grüll Holger Grüll Case Report: Desmoid tumor response to magnetic resonance-guided high intensity focused ultrasound over 4 years Frontiers in Oncology HIFU MR-HIFU focused ultrasound magnetic resonance-guided high intensity focused ultrasound desmoid tumor tumor control |
| title | Case Report: Desmoid tumor response to magnetic resonance-guided high intensity focused ultrasound over 4 years |
| title_full | Case Report: Desmoid tumor response to magnetic resonance-guided high intensity focused ultrasound over 4 years |
| title_fullStr | Case Report: Desmoid tumor response to magnetic resonance-guided high intensity focused ultrasound over 4 years |
| title_full_unstemmed | Case Report: Desmoid tumor response to magnetic resonance-guided high intensity focused ultrasound over 4 years |
| title_short | Case Report: Desmoid tumor response to magnetic resonance-guided high intensity focused ultrasound over 4 years |
| title_sort | case report desmoid tumor response to magnetic resonance guided high intensity focused ultrasound over 4 years |
| topic | HIFU MR-HIFU focused ultrasound magnetic resonance-guided high intensity focused ultrasound desmoid tumor tumor control |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2023.1124244/full |
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