Neurodevelopmental risk factors in schizophrenia
The authors review environmental and neurodevelopmental risk factors for schizophrenic disorders, with emphasis on minor physical anomalies, particularly craniofacial anomalies and dermatoglyphic variations. The high prevalence of these anomalies among schizophrenic subjects supports the neurodevelo...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Associação Brasileira de Divulgação Científica
2001-02-01
|
| Series: | Brazilian Journal of Medical and Biological Research |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000200002 |
| _version_ | 1818898377401696256 |
|---|---|
| author | M.I. Lobato P. Belmonte-de-Abreu D. Knijnik B. Teruchkin E. Ghisolfi A. Henriques |
| author_facet | M.I. Lobato P. Belmonte-de-Abreu D. Knijnik B. Teruchkin E. Ghisolfi A. Henriques |
| author_sort | M.I. Lobato |
| collection | DOAJ |
| description | The authors review environmental and neurodevelopmental risk factors for schizophrenic disorders, with emphasis on minor physical anomalies, particularly craniofacial anomalies and dermatoglyphic variations. The high prevalence of these anomalies among schizophrenic subjects supports the neurodevelopmental theory of the etiology of schizophrenia, since they suggest either genetically or epigenetically controlled faulty embryonic development of structures of ectodermal origin like brain and skin. This may disturb neurodevelopment that in turn may cause these subjects to be at increased risk for the development of schizophrenia and related disorders. The precise confirmation of this theory, at least in some cases, will provide further understanding of these illnesses, allowing easy and inexpensive identification of subjects at risk and providing guidelines for the development of new pharmacological interventions for early treatment and even for primary prevention of the illness. |
| first_indexed | 2024-12-19T19:31:06Z |
| format | Article |
| id | doaj.art-e9d4bbc815e84b40bb050743c0c7c914 |
| institution | Directory Open Access Journal |
| issn | 0100-879X 1414-431X |
| language | English |
| last_indexed | 2024-12-19T19:31:06Z |
| publishDate | 2001-02-01 |
| publisher | Associação Brasileira de Divulgação Científica |
| record_format | Article |
| series | Brazilian Journal of Medical and Biological Research |
| spelling | doaj.art-e9d4bbc815e84b40bb050743c0c7c9142022-12-21T20:08:35ZengAssociação Brasileira de Divulgação CientíficaBrazilian Journal of Medical and Biological Research0100-879X1414-431X2001-02-0134215516310.1590/S0100-879X2001000200002Neurodevelopmental risk factors in schizophreniaM.I. LobatoP. Belmonte-de-AbreuD. KnijnikB. TeruchkinE. GhisolfiA. HenriquesThe authors review environmental and neurodevelopmental risk factors for schizophrenic disorders, with emphasis on minor physical anomalies, particularly craniofacial anomalies and dermatoglyphic variations. The high prevalence of these anomalies among schizophrenic subjects supports the neurodevelopmental theory of the etiology of schizophrenia, since they suggest either genetically or epigenetically controlled faulty embryonic development of structures of ectodermal origin like brain and skin. This may disturb neurodevelopment that in turn may cause these subjects to be at increased risk for the development of schizophrenia and related disorders. The precise confirmation of this theory, at least in some cases, will provide further understanding of these illnesses, allowing easy and inexpensive identification of subjects at risk and providing guidelines for the development of new pharmacological interventions for early treatment and even for primary prevention of the illness.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000200002schizophrenianeurodevelopmental disorderrisk factors |
| spellingShingle | M.I. Lobato P. Belmonte-de-Abreu D. Knijnik B. Teruchkin E. Ghisolfi A. Henriques Neurodevelopmental risk factors in schizophrenia Brazilian Journal of Medical and Biological Research schizophrenia neurodevelopmental disorder risk factors |
| title | Neurodevelopmental risk factors in schizophrenia |
| title_full | Neurodevelopmental risk factors in schizophrenia |
| title_fullStr | Neurodevelopmental risk factors in schizophrenia |
| title_full_unstemmed | Neurodevelopmental risk factors in schizophrenia |
| title_short | Neurodevelopmental risk factors in schizophrenia |
| title_sort | neurodevelopmental risk factors in schizophrenia |
| topic | schizophrenia neurodevelopmental disorder risk factors |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000200002 |
| work_keys_str_mv | AT milobato neurodevelopmentalriskfactorsinschizophrenia AT pbelmontedeabreu neurodevelopmentalriskfactorsinschizophrenia AT dknijnik neurodevelopmentalriskfactorsinschizophrenia AT bteruchkin neurodevelopmentalriskfactorsinschizophrenia AT eghisolfi neurodevelopmentalriskfactorsinschizophrenia AT ahenriques neurodevelopmentalriskfactorsinschizophrenia |