Molecular forms of BMP15 and GDF9 in mammalian species that differ in litter size

Abstract Bone morphogenetic protein (BMP15) and growth differentiation factor (GDF9) are critical for ovarian follicular development and fertility and are associated with litter size in mammals. These proteins initially exist as pre-pro-mature proteins, that are subsequently cleaved into biologicall...

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Bibliographic Details
Main Authors: Gene W. Swinerd, Abdulaziz A. Alhussini, Sarah Sczelecki, Derek Heath, Thomas D. Mueller, Kenneth P. McNatty, Janet L. Pitman
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-49852-1