Hyperglycaemic Hemichorea

Background: Hyperkinetic disorders such as hemichorea can be caused by cerebrovascular, infectious or inflammatory diseases or by metabolic conditions such as hyperglycaemia. Hyperglycaemic hemichorea is a rare movement disorder which is frequently misdiagnosed. It is characterized by involuntary, c...

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Main Authors: Joana Silva Marques, Nuno Monteiro, Ana Nunes, João Machado, João Olivério, Ana Sofia Martins, Antonio Correia
Format: Article
Language:English
Published: SMC MEDIA SRL 2018-02-01
Series:European Journal of Case Reports in Internal Medicine
Subjects:
Online Access:https://www.ejcrim.com/index.php/EJCRIM/article/view/807
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author Joana Silva Marques
Nuno Monteiro
Ana Nunes
João Machado
João Olivério
Ana Sofia Martins
Antonio Correia
author_facet Joana Silva Marques
Nuno Monteiro
Ana Nunes
João Machado
João Olivério
Ana Sofia Martins
Antonio Correia
author_sort Joana Silva Marques
collection DOAJ
description Background: Hyperkinetic disorders such as hemichorea can be caused by cerebrovascular, infectious or inflammatory diseases or by metabolic conditions such as hyperglycaemia. Hyperglycaemic hemichorea is a rare movement disorder which is frequently misdiagnosed. It is characterized by involuntary, continuous, non-patterned movements on one side of the body, basal ganglia lesions seen on head CT or MRI, and clinical improvement after blood glucose normalization. We describe the case of a female patient with uncontrolled diabetes who presented with hemichorea. Case presentation: We report the case of a 69-year-old woman with type 2 diabetes who presented with abnormal movements of the right upper limb. She had no neurological signs other than hemichorea. Her blood glucose level was 349 mg/dl and her glycosylated haemoglobin level (HbA1c) was 10.5%. Head CT and MRI showed no changes in the basal ganglia or ischaemic lesions. The patient was started on insulin and haloperidol with clinical improvement. Conclusion: Larger case series are needed to establish better understanding of the physiopathological mechanisms and diagnostic criteria of hyperglycaemic hemichorea. The most important diagnostic criterion is clinical improvement after glycaemic control.
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spelling doaj.art-e9d70adfbf1140a7a417fbdcaa8c365c2022-12-22T03:18:58ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942018-02-015410.12890/2018_000807807Hyperglycaemic HemichoreaJoana Silva Marques0Nuno Monteiro1Ana Nunes2João Machado3João OlivérioAna Sofia Martins4Antonio Correia5Internal Medicine Department of Tondela-Viseu Hospital Centre, Viseu, PortugalInternal Medicine Department of Tondela-Viseu Hospital Centre, Viseu, PortugalInternal Medicine Department of Tondela-Viseu Hospital Centre, Viseu, PortugalInternal Medicine Department of Tondela-Viseu Hospital Centre, Viseu, PortugalInternal Medicine Department of Tondela-Viseu Hospital Centre, Viseu, PortugalInternal Medicine Department of Tondela-Viseu Hospital Centre, Viseu, PortugalBackground: Hyperkinetic disorders such as hemichorea can be caused by cerebrovascular, infectious or inflammatory diseases or by metabolic conditions such as hyperglycaemia. Hyperglycaemic hemichorea is a rare movement disorder which is frequently misdiagnosed. It is characterized by involuntary, continuous, non-patterned movements on one side of the body, basal ganglia lesions seen on head CT or MRI, and clinical improvement after blood glucose normalization. We describe the case of a female patient with uncontrolled diabetes who presented with hemichorea. Case presentation: We report the case of a 69-year-old woman with type 2 diabetes who presented with abnormal movements of the right upper limb. She had no neurological signs other than hemichorea. Her blood glucose level was 349 mg/dl and her glycosylated haemoglobin level (HbA1c) was 10.5%. Head CT and MRI showed no changes in the basal ganglia or ischaemic lesions. The patient was started on insulin and haloperidol with clinical improvement. Conclusion: Larger case series are needed to establish better understanding of the physiopathological mechanisms and diagnostic criteria of hyperglycaemic hemichorea. The most important diagnostic criterion is clinical improvement after glycaemic control.https://www.ejcrim.com/index.php/EJCRIM/article/view/807Hemichoreadiabetes complicationsmovement disorders
spellingShingle Joana Silva Marques
Nuno Monteiro
Ana Nunes
João Machado
João Olivério
Ana Sofia Martins
Antonio Correia
Hyperglycaemic Hemichorea
European Journal of Case Reports in Internal Medicine
Hemichorea
diabetes complications
movement disorders
title Hyperglycaemic Hemichorea
title_full Hyperglycaemic Hemichorea
title_fullStr Hyperglycaemic Hemichorea
title_full_unstemmed Hyperglycaemic Hemichorea
title_short Hyperglycaemic Hemichorea
title_sort hyperglycaemic hemichorea
topic Hemichorea
diabetes complications
movement disorders
url https://www.ejcrim.com/index.php/EJCRIM/article/view/807
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AT nunomonteiro hyperglycaemichemichorea
AT ananunes hyperglycaemichemichorea
AT joaomachado hyperglycaemichemichorea
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AT anasofiamartins hyperglycaemichemichorea
AT antoniocorreia hyperglycaemichemichorea