Use of Probiotic Bacteria and Bacteriocins as an Alternative to Antibiotics in Aquaculture
In addition to their use in human medicine, antimicrobials are also used in food animals and aquaculture, and their use can be categorized as therapeutic against bacterial infections. The use of antimicrobials in aquaculture may involve a broad environmental application that affects a wide variety o...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-08-01
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| Series: | Microorganisms |
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| Online Access: | https://www.mdpi.com/2076-2607/10/9/1705 |
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| author | Wellison Amorim Pereira Carlos Miguel N. Mendonça Alejandro Villasante Urquiza Viggó Þór Marteinsson Jean Guy LeBlanc Paul D. Cotter Elías Figueroa Villalobos Jaime Romero Ricardo P. S. Oliveira |
| author_facet | Wellison Amorim Pereira Carlos Miguel N. Mendonça Alejandro Villasante Urquiza Viggó Þór Marteinsson Jean Guy LeBlanc Paul D. Cotter Elías Figueroa Villalobos Jaime Romero Ricardo P. S. Oliveira |
| author_sort | Wellison Amorim Pereira |
| collection | DOAJ |
| description | In addition to their use in human medicine, antimicrobials are also used in food animals and aquaculture, and their use can be categorized as therapeutic against bacterial infections. The use of antimicrobials in aquaculture may involve a broad environmental application that affects a wide variety of bacteria, promoting the spread of bacterial resistance genes. Probiotics and bacteriocins, antimicrobial peptides produced by some types of lactic acid bacteria (LAB), have been successfully tested in aquatic animals as alternatives to control bacterial infections. Supplementation might have beneficial impacts on the intestinal microbiota, immune response, development, and/or weight gain, without the issues associated with antibiotic use. Thus, probiotics and bacteriocins represent feasible alternatives to antibiotics. Here, we provide an update with respect to the relevance of aquaculture in the animal protein production sector, as well as the present and future challenges generated by outbreaks and antimicrobial resistance, while highlighting the potential role of probiotics and bacteriocins to address these challenges. In addition, we conducted data analysis using a simple linear regression model to determine whether a linear relationship exists between probiotic dose added to feed and three variables of interest selected, including specific growth rate, feed conversion ratio, and lysozyme activity. |
| first_indexed | 2024-03-09T23:07:22Z |
| format | Article |
| id | doaj.art-e9d77e6b1bef47fdb87959b4c1992811 |
| institution | Directory Open Access Journal |
| issn | 2076-2607 |
| language | English |
| last_indexed | 2024-03-09T23:07:22Z |
| publishDate | 2022-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj.art-e9d77e6b1bef47fdb87959b4c19928112023-11-23T17:51:50ZengMDPI AGMicroorganisms2076-26072022-08-01109170510.3390/microorganisms10091705Use of Probiotic Bacteria and Bacteriocins as an Alternative to Antibiotics in AquacultureWellison Amorim Pereira0Carlos Miguel N. Mendonça1Alejandro Villasante Urquiza2Viggó Þór Marteinsson3Jean Guy LeBlanc4Paul D. Cotter5Elías Figueroa Villalobos6Jaime Romero7Ricardo P. S. Oliveira8Microbial Biomolecules Laboratory, Faculty of Pharmaceutical Sciences, São Paulo University, Rua do Lago 250, Cidade Universitária, São Paulo 05508-000, SP, BrazilMicrobial Biomolecules Laboratory, Faculty of Pharmaceutical Sciences, São Paulo University, Rua do Lago 250, Cidade Universitária, São Paulo 05508-000, SP, BrazilFacultad de Medicina Veterinaria y Agronomía, Universidad de Las Américas, Santiago 7500000, ChileMatís OHF, Microbiology Research Group, Vínlandsleið 12, 113 Reykjavík, IcelandCentro de Referencia para Lactobacilos (CERELA-CONICET), San Miguel de Tucuman T4000, ArgentinaTeagasc Food Research Centre, Moorepark, APC Microbiome Ireland, T12 K8AF Cork, IrelandNucleus of Research in Food Production, Faculty of Natural Resources, Catholic University of Temuco, Temuco 4780000, ChileLaboratorio de Biotecnología de Alimentos, Instituto de Nutricion y Tecnologia de los Alimentos (INTA), Universidad de Chile, El Libano 5524, Santiago 783090, ChileMicrobial Biomolecules Laboratory, Faculty of Pharmaceutical Sciences, São Paulo University, Rua do Lago 250, Cidade Universitária, São Paulo 05508-000, SP, BrazilIn addition to their use in human medicine, antimicrobials are also used in food animals and aquaculture, and their use can be categorized as therapeutic against bacterial infections. The use of antimicrobials in aquaculture may involve a broad environmental application that affects a wide variety of bacteria, promoting the spread of bacterial resistance genes. Probiotics and bacteriocins, antimicrobial peptides produced by some types of lactic acid bacteria (LAB), have been successfully tested in aquatic animals as alternatives to control bacterial infections. Supplementation might have beneficial impacts on the intestinal microbiota, immune response, development, and/or weight gain, without the issues associated with antibiotic use. Thus, probiotics and bacteriocins represent feasible alternatives to antibiotics. Here, we provide an update with respect to the relevance of aquaculture in the animal protein production sector, as well as the present and future challenges generated by outbreaks and antimicrobial resistance, while highlighting the potential role of probiotics and bacteriocins to address these challenges. In addition, we conducted data analysis using a simple linear regression model to determine whether a linear relationship exists between probiotic dose added to feed and three variables of interest selected, including specific growth rate, feed conversion ratio, and lysozyme activity.https://www.mdpi.com/2076-2607/10/9/1705probioticbacteriocinantibioticaquaculturebiotechnology |
| spellingShingle | Wellison Amorim Pereira Carlos Miguel N. Mendonça Alejandro Villasante Urquiza Viggó Þór Marteinsson Jean Guy LeBlanc Paul D. Cotter Elías Figueroa Villalobos Jaime Romero Ricardo P. S. Oliveira Use of Probiotic Bacteria and Bacteriocins as an Alternative to Antibiotics in Aquaculture Microorganisms probiotic bacteriocin antibiotic aquaculture biotechnology |
| title | Use of Probiotic Bacteria and Bacteriocins as an Alternative to Antibiotics in Aquaculture |
| title_full | Use of Probiotic Bacteria and Bacteriocins as an Alternative to Antibiotics in Aquaculture |
| title_fullStr | Use of Probiotic Bacteria and Bacteriocins as an Alternative to Antibiotics in Aquaculture |
| title_full_unstemmed | Use of Probiotic Bacteria and Bacteriocins as an Alternative to Antibiotics in Aquaculture |
| title_short | Use of Probiotic Bacteria and Bacteriocins as an Alternative to Antibiotics in Aquaculture |
| title_sort | use of probiotic bacteria and bacteriocins as an alternative to antibiotics in aquaculture |
| topic | probiotic bacteriocin antibiotic aquaculture biotechnology |
| url | https://www.mdpi.com/2076-2607/10/9/1705 |
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