Invariant NKT cells are more abundant in peanut-allergic adults and a subset of CD8+ iNKT cells are depleted after peanut oil exposure

Invariant NKT cells are more abundant in peanut-allergic adults and a subset of CD8+ iNKT cells are depleted after peanut oil exposure

IntroductionPeanut allergy is one of the most prevalent food allergies globally. Currently, most research into the mechanisms involved in protein allergy focuses on the protein allergens under investigation, and information on the function of accompanying compounds, such as lipids, is scarce. Thus,...

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Bibliographic Details
Main Authors: Georgina V. Hopkins, Stella Cochrane, David Onion, Lucy C. Fairclough
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Immunology
Subjects:
dendritic cells
invariant NKT cells
allergic sensitization
peanut oil
α-galactosylceramide
CD1d
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1293158/full

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