Treatment of Advanced Squamous Cell Lung Cancer

Lung cancer is the deadliest cancer in the worldwide. Non-small cell lung cancer (NSCLC) accounts for 85% of lung tumor diagnoses. Squamous cell lung cancer (SQCLC) is a common pathological type, almost 20%-30% of NSCLC. Surgery, chemotherapy, and molecular targeted therapies are the mainstay of tre...

Full description

Bibliographic Details
Main Authors: Yixiang ZHU, Puyuan XING, Junling LI
Format: Article
Language:zho
Published: Chinese Anti-Cancer Association; Chinese Antituberculosis Association 2016-10-01
Series:Chinese Journal of Lung Cancer
Subjects:
Online Access:http://dx.doi.org/10.3779/j.issn.1009-3419.2016.10.10
_version_ 1819181069876854784
author Yixiang ZHU
Puyuan XING
Junling LI
author_facet Yixiang ZHU
Puyuan XING
Junling LI
author_sort Yixiang ZHU
collection DOAJ
description Lung cancer is the deadliest cancer in the worldwide. Non-small cell lung cancer (NSCLC) accounts for 85% of lung tumor diagnoses. Squamous cell lung cancer (SQCLC) is a common pathological type, almost 20%-30% of NSCLC. Surgery, chemotherapy, and molecular targeted therapies are the mainstay of treatment for patients with SQCLC. But most patients are diagnosed at advanced stage so that they miss the chance of operation. While noteworthy outcomes have improved with adenocarcinoma of lung with epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), a therapeutic plateau for advanced squamous cell lung cancer patients are still not solved. EGFR-TKIs are unsuitable for or mostly ineffective in advanced SQCLC. Patients with advanced SQCLC ramain treated with platinum based chemotherapy. This reciew systematicly describe the treatment of squamous cell carcinoma of the lung.
first_indexed 2024-12-22T22:24:23Z
format Article
id doaj.art-e9db3e756c044d869dc98f425ba6a87b
institution Directory Open Access Journal
issn 1009-3419
1999-6187
language zho
last_indexed 2024-12-22T22:24:23Z
publishDate 2016-10-01
publisher Chinese Anti-Cancer Association; Chinese Antituberculosis Association
record_format Article
series Chinese Journal of Lung Cancer
spelling doaj.art-e9db3e756c044d869dc98f425ba6a87b2022-12-21T18:10:36ZzhoChinese Anti-Cancer Association; Chinese Antituberculosis AssociationChinese Journal of Lung Cancer1009-34191999-61872016-10-011910pagepage10.3779/j.issn.1009-3419.2016.10.10Treatment of Advanced Squamous Cell Lung CancerYixiang ZHU0Puyuan XING1Junling LI2National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, ChinaNational Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, ChinaNational Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, ChinaLung cancer is the deadliest cancer in the worldwide. Non-small cell lung cancer (NSCLC) accounts for 85% of lung tumor diagnoses. Squamous cell lung cancer (SQCLC) is a common pathological type, almost 20%-30% of NSCLC. Surgery, chemotherapy, and molecular targeted therapies are the mainstay of treatment for patients with SQCLC. But most patients are diagnosed at advanced stage so that they miss the chance of operation. While noteworthy outcomes have improved with adenocarcinoma of lung with epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), a therapeutic plateau for advanced squamous cell lung cancer patients are still not solved. EGFR-TKIs are unsuitable for or mostly ineffective in advanced SQCLC. Patients with advanced SQCLC ramain treated with platinum based chemotherapy. This reciew systematicly describe the treatment of squamous cell carcinoma of the lung.http://dx.doi.org/10.3779/j.issn.1009-3419.2016.10.10Lung neoplasmsChemotherapyTargeted therapy
spellingShingle Yixiang ZHU
Puyuan XING
Junling LI
Treatment of Advanced Squamous Cell Lung Cancer
Chinese Journal of Lung Cancer
Lung neoplasms
Chemotherapy
Targeted therapy
title Treatment of Advanced Squamous Cell Lung Cancer
title_full Treatment of Advanced Squamous Cell Lung Cancer
title_fullStr Treatment of Advanced Squamous Cell Lung Cancer
title_full_unstemmed Treatment of Advanced Squamous Cell Lung Cancer
title_short Treatment of Advanced Squamous Cell Lung Cancer
title_sort treatment of advanced squamous cell lung cancer
topic Lung neoplasms
Chemotherapy
Targeted therapy
url http://dx.doi.org/10.3779/j.issn.1009-3419.2016.10.10
work_keys_str_mv AT yixiangzhu treatmentofadvancedsquamouscelllungcancer
AT puyuanxing treatmentofadvancedsquamouscelllungcancer
AT junlingli treatmentofadvancedsquamouscelllungcancer