Monocytes and Macrophages Serve as Potent Prostaglandin D<sub>2</sub> Sources during Acute, Non-Allergic Pulmonary Inflammation

Monocytes and Macrophages Serve as Potent Prostaglandin D<sub>2</sub> Sources during Acute, Non-Allergic Pulmonary Inflammation

Acute respiratory inflammation, most commonly resulting from bacterial or viral infection, is one of the leading causes of death and disability worldwide. The inflammatory lipid mediator prostaglandin D<sub>2</sub> (PGD<sub>2</sub>) and its rate-limiting enzyme, hematopoietic...

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Bibliographic Details
Main Authors: Sonja Rittchen, Katharina Jandl, Ilse Lanz, Bernhard Reiter, Nerea Ferreirós, Daniel Kratz, Jörg Lindenmann, Luka Brcic, Thomas Bärnthaler, Reham Atallah, Horst Olschewski, Eva M. Sturm, Akos Heinemann
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
prostaglandin D<sub>2</sub>
hPGDS
lipopolysaccharide
acute lung injury
mononuclear phagocytes
precision-cut lung slices
Online Access:https://www.mdpi.com/1422-0067/22/21/11697

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