Interleukin‐2/anti‐interleukin‐2 immune complex attenuates cold ischemia‐reperfusion injury after kidney transplantation by increasing renal regulatory T cells

Interleukin‐2/anti‐interleukin‐2 immune complex attenuates cold ischemia‐reperfusion injury after kidney transplantation by increasing renal regulatory T cells

Abstract Background Cold ischemia‐reperfusion injury (IRI) is an unavoidable complication of kidney transplantation. We investigated the role of regulatory T cells (Treg) in cold IRI and whether the interleukin (IL)‐2/anti‐IL‐2 antibody complex (IL‐2C) can ameliorate cold IRI. Methods We developed a...

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Bibliographic Details
Main Authors:	Joon Young Jang, Hyung Woo Kim, Ji‐Jing Yan, Tae Kyeom Kang, Wook‐Bin Lee, Beom Seok Kim, Jaeseok Yang
Format:	Article
Language:	English
Published:	Wiley 2024-03-01
Series:	Clinical and Translational Medicine
Subjects:	cold ischemia‐reperfusion injury IL‐2/anti‐IL‐2 immune complex kidney transplantation regulatory T cells
Online Access:	https://doi.org/10.1002/ctm2.1631

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