Psychogenic dyspnea and hypocapnia in men with ischemic heart disease before and after CABG
The goal of the study was to compare the rate of psychogenic dyspnea (PD) and hypocapnia in patients with ischemic heart disease (IHD) before and after CABG. We studied the objective signs of PD and hypocapnia, such as psychogenic dyspnea coefficient (PDC) and СО <sub>2</sub> concentrati...
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| Format: | Article |
| Language: | English |
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Meshalkin National Medical Research Center
2018-06-01
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| Series: | Патология кровообращения и кардиохирургия |
| Subjects: | |
| Online Access: | https://journalmeshalkin.ru/index.php/heartjournal/article/view/564 |
| _version_ | 1797726188543672320 |
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| author | O. V. Grishin N. N. Averko V. G. Grishin I. G. Zhilina Yu. V. Kovalenko |
| author_facet | O. V. Grishin N. N. Averko V. G. Grishin I. G. Zhilina Yu. V. Kovalenko |
| author_sort | O. V. Grishin |
| collection | DOAJ |
| description | The goal of the study was to compare the rate of psychogenic dyspnea (PD) and hypocapnia in patients with ischemic heart disease (IHD) before and after CABG. We studied the objective signs of PD and hypocapnia, such as psychogenic dyspnea coefficient (PDC) and СО <sub>2</sub> concentration in the expired air finite portion (FetCО <sub>2</sub>) in 47 male patients with IHD and 34 healthy men by using spirometry and capnometry. We also performed a comparative analysis of the above-mentioned parameters before and after CABG. The arrhythmic breathing rate (PDC>40) in patients with IHD was 2.6 times higher than that in healthy men, and the hypocapnia rate (FetCО <sub>2</sub><4.5%) was 3.6 times higher than that in the control group. The data obtained were confirmed by the group mean values of PDC and FetCО <sub>2</sub>. Thus, PDC in the IHD cohort was significantly higher, and FetCО <sub>2</sub> lower than in healthy men (4.60.4 and 5.20.3 respectively, р<0.05). On the 8-10 <sup>th</sup> postoperative day there was a 1.3 times increase in patients with PDC>40, and a 1.7 times increase in hypocapnia patients, with the mean FetCО <sub>2</sub> level decreasing from 4.60.4 before surgery down to 4.00.7 after CABG (р<0,05). Thus, psychogenic dyspnea or neurogenic hyperventilation (NH), as well as the resulted hypocapnia, are documented in IHD patients. Because of its negative cardiovascular effects, NH requires timely diagnosis and correction before and after coronary revascularization surgery. |
| first_indexed | 2024-03-12T10:42:10Z |
| format | Article |
| id | doaj.art-e9e66cab9cd7412e8fcf704c47407251 |
| institution | Directory Open Access Journal |
| issn | 1681-3472 2500-3119 |
| language | English |
| last_indexed | 2024-03-12T10:42:10Z |
| publishDate | 2018-06-01 |
| publisher | Meshalkin National Medical Research Center |
| record_format | Article |
| series | Патология кровообращения и кардиохирургия |
| spelling | doaj.art-e9e66cab9cd7412e8fcf704c474072512023-09-02T08:03:36ZengMeshalkin National Medical Research CenterПатология кровообращения и кардиохирургия1681-34722500-31192018-06-01161394210.21688/1681-3472-2012-1-39-421161Psychogenic dyspnea and hypocapnia in men with ischemic heart disease before and after CABGO. V. Grishin0N. N. AverkoV. G. GrishinI. G. ZhilinaYu. V. Kovalenko1НИИ физиологии СО РАМННИИ физиологии СО РАМНThe goal of the study was to compare the rate of psychogenic dyspnea (PD) and hypocapnia in patients with ischemic heart disease (IHD) before and after CABG. We studied the objective signs of PD and hypocapnia, such as psychogenic dyspnea coefficient (PDC) and СО <sub>2</sub> concentration in the expired air finite portion (FetCО <sub>2</sub>) in 47 male patients with IHD and 34 healthy men by using spirometry and capnometry. We also performed a comparative analysis of the above-mentioned parameters before and after CABG. The arrhythmic breathing rate (PDC>40) in patients with IHD was 2.6 times higher than that in healthy men, and the hypocapnia rate (FetCО <sub>2</sub><4.5%) was 3.6 times higher than that in the control group. The data obtained were confirmed by the group mean values of PDC and FetCО <sub>2</sub>. Thus, PDC in the IHD cohort was significantly higher, and FetCО <sub>2</sub> lower than in healthy men (4.60.4 and 5.20.3 respectively, р<0.05). On the 8-10 <sup>th</sup> postoperative day there was a 1.3 times increase in patients with PDC>40, and a 1.7 times increase in hypocapnia patients, with the mean FetCО <sub>2</sub> level decreasing from 4.60.4 before surgery down to 4.00.7 after CABG (р<0,05). Thus, psychogenic dyspnea or neurogenic hyperventilation (NH), as well as the resulted hypocapnia, are documented in IHD patients. Because of its negative cardiovascular effects, NH requires timely diagnosis and correction before and after coronary revascularization surgery.https://journalmeshalkin.ru/index.php/heartjournal/article/view/564ПСИХОГЕННАЯ ОДЫШКАГИПОКАПНИЯИШЕМИЧЕСКАЯ БОЛЕЗНЬ СЕРДЦАДЫХАНИЕ |
| spellingShingle | O. V. Grishin N. N. Averko V. G. Grishin I. G. Zhilina Yu. V. Kovalenko Psychogenic dyspnea and hypocapnia in men with ischemic heart disease before and after CABG Патология кровообращения и кардиохирургия ПСИХОГЕННАЯ ОДЫШКА ГИПОКАПНИЯ ИШЕМИЧЕСКАЯ БОЛЕЗНЬ СЕРДЦА ДЫХАНИЕ |
| title | Psychogenic dyspnea and hypocapnia in men with ischemic heart disease before and after CABG |
| title_full | Psychogenic dyspnea and hypocapnia in men with ischemic heart disease before and after CABG |
| title_fullStr | Psychogenic dyspnea and hypocapnia in men with ischemic heart disease before and after CABG |
| title_full_unstemmed | Psychogenic dyspnea and hypocapnia in men with ischemic heart disease before and after CABG |
| title_short | Psychogenic dyspnea and hypocapnia in men with ischemic heart disease before and after CABG |
| title_sort | psychogenic dyspnea and hypocapnia in men with ischemic heart disease before and after cabg |
| topic | ПСИХОГЕННАЯ ОДЫШКА ГИПОКАПНИЯ ИШЕМИЧЕСКАЯ БОЛЕЗНЬ СЕРДЦА ДЫХАНИЕ |
| url | https://journalmeshalkin.ru/index.php/heartjournal/article/view/564 |
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